Randomised controlled trials
90 randomised controlled trials concerning Ayurvedic materia medica, each with a PubMed identifier and the herbs or formulations it concerns. Controlled trials in people.
- Systematic reviews and meta-analyses (149)
- Randomised controlled trials (90)
- Other clinical studies and reviews (1066)
- Laboratory and animal studies (1587)
- 2026. Improved HDL, LDL and total cholesterol levels following a 3-month administration of Mentha spicata leaf extract and Amaranthus caudatus seed flour extracts, flavonoids and B vitamins. A placebo-controlled, double-blind, randomized clinical trial Nutrition, metabolism, and cardiovascular diseases : NMCD. PMID 41519619 · doi:10.1016/j.numecd.2025.104470
- 2025. A Standardized Asparagus Racemosus Root Extract Improves Hormonal Balance and Menstrual Health and Reduces Vasomotor Symptoms in Perimenopausal Women: A Randomized, Double-Blind, Placebo-Controlled Study Journal of the American Nutrition Association. PMID 40434025 · doi:10.1080/27697061.2025.2510474
- 2025. Anti-inflammatory and antimicrobial efficacy of coconut oil for periodontal pathogens: a triple-blind randomized clinical trial Clinical oral investigations. PMID 40085302 · doi:10.1007/s00784-025-06267-8
- 2025. Bitter gourd (Momordica charantia L.) supplementation for twelve weeks improves biomarkers of glucose homeostasis in a prediabetic population Journal of ethnopharmacology. PMID 40199408 · doi:10.1016/j.jep.2025.119756
- 2025. Comparative efficacy of Mucuna pruriens and conventional levodopa in Parkinson's disease: a randomized controlled trial on pharmacokinetics and clinical perspectives from Asia Journal of neural transmission (Vienna, Austria : 1996). PMID 40137945 · doi:10.1007/s00702-025-02914-2
- 2025. Comparison of the effect of ice sucking containing peppermint (Mentha piperita L.) with cardamom (Elettaria cardamomum) extract on nausea, vomiting, and drug request after laparoscopic cholecystectomy Explore (New York, N.Y.). PMID 40967081 · doi:10.1016/j.explore.2025.103261
- 2025. Effects of Acacia catechu and Scutellaria baicalensis extract on cognitive function in a healthy adult population: a double-blind, randomized, placebo-controlled trial Nutritional neuroscience. PMID 39701593 · doi:10.1080/1028415X.2024.2442425
- 2025. Effects of Moringa oleifera leaves on the blood glucose, blood pressure, and lipid profile of type 2 diabetic subjects: A parallel group randomized clinical trial of efficacy Nutrition and health. PMID 37229639 · doi:10.1177/02601060231176873
- 2025. Efficacy and safety of Cyperus rotundus extract on weight management in obese individuals: A randomized, double-blind, placebo-controlled study Medicine. PMID 41305713 · doi:10.1097/MD.0000000000045666
- 2025. Evaluation of the add on effect of Majoone Sarkhas with levothyroxine in primary hypothyroidism: a randomized standard control adjuvant clinical study Drug metabolism and personalized therapy. PMID 39976613 · doi:10.1515/dmpt-2024-0096
- 2025. Shatavari (Asparagus racemosus Willd) root extract for postpartum lactation: A randomised, double-blind, placebo-controlled study Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. PMID 41055223 · doi:10.1080/01443615.2025.2564168
- 2025. The Effects of a Bacopa monnieri Extract (Bacumen(®)) on Cognition, Stress, and Fatigue in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial Clinical drug investigation. PMID 41091332 · doi:10.1007/s40261-025-01492-1
- 2024. Clinical efficacy of Kuanxiong aerosol for patients with prehospital chest pain: A randomized controlled trial Phytomedicine : international journal of phytotherapy and phytopharmacology. PMID 38091825 · doi:10.1016/j.phymed.2023.155206
- 2024. Dietary supplementation of Sida rhombifolia enhances the plasma antioxidation and modulates gut microbiota in Anyi tile-like grey chickens Journal of animal physiology and animal nutrition. PMID 38943520 · doi:10.1111/jpn.14013
- 2024. Efficacy and Tolerability of a Food Supplement Based on Zea mays L., Gymnema sylvestre (Retz.) R.br.ex Sm, Zinc and Chromium for the Maintenance of Normal Carbohydrate Metabolism: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Nutrients. PMID 39125340 · doi:10.3390/nu16152459
- 2024. Evaluation of the effectiveness of Berberis integerrima Bunge root extract combined with spearmint essential oil in the treatment of acne vulgaris: A randomized controlled clinical trial Journal of cosmetic dermatology. PMID 38545754 · doi:10.1111/jocd.16291
- 2024. Evaluation of the efficacy and safety of cannabidiol-rich cannabis extract in children with autism spectrum disorder: randomized, double-blind, and placebo-controlled clinical trial Trends in psychiatry and psychotherapy. PMID 35617670 · doi:10.47626/2237-6089-2021-0396
- 2024. Phyllanthus emblica fruit extract alleviates halitosis and reduces the inflammatory response to oral bacteria Journal of applied oral science : revista FOB. PMID 38922243 · doi:10.1590/1678-7757-2024-0047
- 2024. The effect of an oral product containing Amla fruit (Phyllanthus emblica L.) on female androgenetic alopecia: A randomized controlled trial Journal of ethnopharmacology. PMID 37487962 · doi:10.1016/j.jep.2023.116958
- 2023. Dietary effects of Gmelina arborea × Panicum maximum forages on digestibility and haematological characteristics of rams Tropical animal health and production. PMID 37014584 · doi:10.1007/s11250-023-03558-8
- 2023. Efficacy and Safety of Aflapin®, a Novel Boswellia Serrata Extract, in the Treatment of Osteoarthritis of the Knee: A Short-Term 30-Day Randomized, Double-Blind, Placebo-Controlled Clinical Study Journal of the American Nutrition Association. PMID 35512759 · doi:10.1080/07315724.2021.2014370
- 2023. Efficacy of Andrographis paniculata spray in acute pharyngitis: A randomized controlled trial Drug discoveries & therapeutics. PMID 37821383 · doi:10.5582/ddt.2023.01053
- 2022. Fat reducing effects of Nelumbo nucifera leaf extract in overweight patients Natural product research. PMID 34852695 · doi:10.1080/14786419.2021.2010196
- 2022. Rosa damascena together with brown sugar mitigate functional constipation in children over 12 months old: A double-blind randomized controlled trial Journal of ethnopharmacology. PMID 35963416 · doi:10.1016/j.jep.2022.115582
- 2022. The Effect of a 14-Day gymnema sylvestre Intervention to Reduce Sugar Cravings in Adults Nutrients. PMID 36558446 · doi:10.3390/nu14245287
- 2022. The effect of Cassia fistula L. syrup in geriatrics constipation in comparison with the lactulose: A randomized clinical trial Journal of ethnopharmacology. PMID 35798138 · doi:10.1016/j.jep.2022.115466
- 2022. The effectiveness of Cyperus rotundus essential oil in reducing the side effects of laser hair removal Journal of cosmetic dermatology. PMID 34132024 · doi:10.1111/jocd.14301
- 2022. The effects of add-on therapy of Phyllanthus Emblica (Amla) on laboratory confirmed COVID-19 Cases: A randomized, double-blind, controlled trial Complementary therapies in medicine. PMID 35093510 · doi:10.1016/j.ctim.2022.102808
- 2022. Topical Cyperus rotundus essential oil for treatment of axillary hyperpigmentation: a randomized, double-blind, active- and placebo-controlled study Clinical and experimental dermatology. PMID 34618367 · doi:10.1111/ced.14959
- 2021. A randomized, double-blind, dose-ranging, pilot trial of piperine with resveratrol on the effects on serum levels of resveratrol European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). PMID 32868637 · doi:10.1097/CEJ.0000000000000621
- 2021. Crude saponin extract from Sesbania grandiflora (L.) Pers pod meal could modulate ruminal fermentation, and protein utilization, as well as mitigate methane production Tropical animal health and production. PMID 33674897 · doi:10.1007/s11250-021-02644-z
- 2021. Effect of Gymnema sylvestre Administration on Glycemic Control, Insulin Secretion, and Insulin Sensitivity in Patients with Impaired Glucose Tolerance Journal of medicinal food. PMID 32460589 · doi:10.1089/jmf.2020.0024
- 2021. Guggulu and Triphala for the Treatment of Hypercholesterolaemia: A Placebo-Controlled, Double-Blind, Randomised Trial Complementary medicine research. PMID 33242870 · doi:10.1159/000510985
- 2021. The Effects of 6 Weeks of Tribulus terrestris L. Supplementation on Body Composition, Hormonal Response, Perceived Exertion, and CrossFit® Performance: A Randomized, Single-Blind, Placebo-Controlled Study Nutrients. PMID 34836225 · doi:10.3390/nu13113969
- 2021. The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial Pharmaceutical biology. PMID 33899689 · doi:10.1080/13880209.2021.1893349
- 2020. Efficacy of a vaginal tablet as a Persian medicine product on vulvovaginal candidiasis: a double-blind, randomised, placebo-controlled trial Pharmaceutical biology. PMID 32615837 · doi:10.1080/13880209.2020.1784236
- 2020. Efficacy of Nardostachys jatamansi (D.Don) DC in essential hypertension: A randomized controlled study Complementary therapies in medicine. PMID 33066862 · doi:10.1016/j.ctim.2020.102532
- 2020. Hypoglycemic efficacy and safety of Momordica charantia (bitter melon) in patients with type 2 diabetes mellitus Complementary therapies in medicine. PMID 32951763 · doi:10.1016/j.ctim.2020.102524
- 2020. Modulatory Effects of Triphala and Manjistha Dietary Supplementation on Human Gut Microbiota: A Double-Blind, Randomized, Placebo-Controlled Pilot Study Journal of alternative and complementary medicine (New York, N.Y.). PMID 32955913 · doi:10.1089/acm.2020.0148
- 2019. A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee Phytotherapy research : PTR. PMID 30838706 · doi:10.1002/ptr.6338
- 2019. A randomized controlled double blinded trial to evaluate efficacy of oral administration of black strap molasses (sugarcane extract) in comparison with polyethylene glycol on pediatric functional constipation Journal of ethnopharmacology. PMID 30946967 · doi:10.1016/j.jep.2019.111845
- 2019. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study Medicine. PMID 31517876 · doi:10.1097/MD.0000000000017186
- 2019. Effects of topical sesame (Sesamum indicum) oil on the pain severity of chemotherapy-induced phlebitis in patients with colorectal cancer: A randomized controlled trial Complementary therapies in clinical practice. PMID 31003690 · doi:10.1016/j.ctcp.2019.01.016
- 2019. Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial Phytomedicine : international journal of phytotherapy and phytopharmacology. PMID 31055046 · doi:10.1016/j.phymed.2019.152828
- 2019. Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing The British journal of dermatology. PMID 29947134 · doi:10.1111/bjd.16918
- 2019. The efficacy of a Persian herbal formulation on functional bloating: A double-blind randomized controlled trial Journal of integrative medicine. PMID 31201146 · doi:10.1016/j.joim.2019.05.007
- 2018. A randomized comparative study of herbal decoction of Cassia fistula Linn pod's pericarp and Myristica fragrans Houtt arils vs. mefenamic acid in spasmodic dysmenorrhoea Journal of complementary & integrative medicine. PMID 30312165 · doi:10.1515/jcim-2018-0105
- 2018. Beneficial effect of Burdock complex on asymptomatic Helicobacter pylori-infected subjects: A randomized, double-blind placebo-controlled clinical trial Helicobacter. PMID 29520881 · doi:10.1111/hel.12469
- 2018. Combined extracts of Garcinia mangostana fruit rind and Cinnamomum tamala leaf supplementation enhances muscle strength and endurance in resistance trained males Journal of the International Society of Sports Nutrition. PMID 30348185 · doi:10.1186/s12970-018-0257-4
- 2018. Daily intake of Mucuna pruriens in advanced Parkinson's disease: A 16-week, noninferiority, randomized, crossover, pilot study Parkinsonism & related disorders. PMID 29352722 · doi:10.1016/j.parkreldis.2018.01.014
- 2018. Efficacy of grape seed extract gel in the treatment of chronic periodontitis: A randomized clinical study Journal of investigative and clinical dentistry. PMID 29349878 · doi:10.1111/jicd.12318
- 2018. Spearmint Extract Improves Working Memory in Men and Women with Age-Associated Memory Impairment Journal of alternative and complementary medicine (New York, N.Y.). PMID 29314866 · doi:10.1089/acm.2016.0379
- 2018. Urox containing concentrated extracts of Crataeva nurvala stem bark, Equisetum arvense stem and Lindera aggregata root, in the treatment of symptoms of overactive bladder and urinary incontinence: a phase 2, randomised, double-blind placebo controlled trial BMC complementary and alternative medicine. PMID 29385990 · doi:10.1186/s12906-018-2101-4
- 2018. Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil with In Vitro Properties Relevant to Central Nervous System Function Nutrients. PMID 30087294 · doi:10.3390/nu10081029
- 2017. Cardamom supplementation improves inflammatory and oxidative stress biomarkers in hyperlipidemic, overweight, and obese pre-diabetic women: a randomized double-blind clinical trial Journal of the science of food and agriculture. PMID 28480505 · doi:10.1002/jsfa.8414
- 2017. Cardioprotective Effects of Pomegranate (Punica granatum) Juice in Patients with Ischemic Heart Disease Phytotherapy research : PTR. PMID 28913846 · doi:10.1002/ptr.5901
- 2017. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial Phytotherapy research : PTR. PMID 28685911 · doi:10.1002/ptr.5858
- 2017. Effect of E-OJ-01 on Cardiac Conditioning in Young Exercising Adults: A Randomized Controlled Trial American journal of therapeutics. PMID 27930383 · doi:10.1097/MJT.0000000000000542
- 2017. Effect of Gymnema sylvestre Administration on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion Journal of medicinal food. PMID 28459647 · doi:10.1089/jmf.2017.0001
- 2017. Efficacy of Tamarindus indicus, Melia azadirach and Santalum album in syndromic management of abnormal vaginal discharge: A single-blind randomised controlled trial Journal of complementary & integrative medicine. PMID 29257757 · doi:10.1515/jcim-2015-0023
- 2017. The effects of green cardamom on blood glucose indices, lipids, inflammatory factors, paraxonase-1, sirtuin-1, and irisin in patients with nonalcoholic fatty liver disease and obesity: study protocol for a randomized controlled trial Trials. PMID 28592311 · doi:10.1186/s13063-017-1979-3
- 2016. Clinical efficacy of water extract of stem bark of Terminalia arjuna (Roxb. ex DC.) Wight & Arn. in patients of chronic heart failure: a double-blind, randomized controlled trial Phytomedicine : international journal of phytotherapy and phytopharmacology. PMID 26988798 · doi:10.1016/j.phymed.2016.02.007
- 2016. Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study The aging male : the official journal of the International Society for the Study of the Aging Male. PMID 26791805 · doi:10.3109/13685538.2015.1135323
- 2016. Trachyspermum ammi 10 % topical cream versus placebo on neuropathic pain, a randomized, double-blind, placebo-controlled trial Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. PMID 27166709 · doi:10.1007/s10072-016-2600-3
- 2015. Effect of Achyranthes aspera, 0.2% Aqueous Chlorhexidine Gluconate and Punica granatum Oral Rinse on the Levels of Salivary Streptococcus mutans in 8 to 12 Years Old Children The journal of contemporary dental practice. PMID 26718299 · doi:10.5005/jp-journals-10024-1779
- 2014. A combination of Scutellaria baicalensis and Acacia catechu extracts for short-term symptomatic relief of joint discomfort associated with osteoarthritis of the knee Journal of medicinal food. PMID 24611484 · doi:10.1089/jmf.2013.0010
- 2014. Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions: a randomized controlled trial Complementary therapies in medicine. PMID 24559814 · doi:10.1016/j.ctim.2013.08.014
- 2014. Topical Cyperus rotundus oil: a new therapeutic modality with comparable efficacy to Alexandrite laser photo-epilation Aesthetic surgery journal. PMID 24408514 · doi:10.1177/1090820X13518801
- 2013. Effects of Berberis aristata/Silybum marianum association on metabolic parameters and adipocytokines in overweight dyslipidemic patients Journal of biological regulators and homeostatic agents. PMID 24152839
- 2013. Green leafy porridges: how good are they in controlling glycaemic response? International journal of food sciences and nutrition. PMID 22849311 · doi:10.3109/09637486.2012.710895
- 2013. Treatment of irritable bowel syndrome using a selected herbal combination of Iraqi folk medicines Journal of ethnopharmacology. PMID 23707209 · doi:10.1016/j.jep.2013.05.034
- 2012. Effect of Pueraria tuberosa DC. (Indian Kudzu) on blood pressure, fibrinolysis and oxidative stress in patients with stage 1 hypertension Pakistan journal of biological sciences : PJBS. PMID 24171260 · doi:10.3923/pjbs.2012.742.747
- 2012. Influence of different supplements and sugarcane (Saccharum officinarum L.) cultivars on intake, digestible variables and methane production of dairy heifers under tropical conditions Tropical animal health and production. PMID 22476735 · doi:10.1007/s11250-012-0136-y
- 2011. Anthelmintic activity of Trianthema portulacastrum L. and Musa paradisiaca L. against gastrointestinal nematodes of sheep Veterinary parasitology. PMID 21440370 · doi:10.1016/j.vetpar.2011.02.022
- 2011. Antihyperlipidemic effects of Salvia officinalis L. leaf extract in patients with hyperlipidemia: a randomized double-blind placebo-controlled clinical trial Phytotherapy research : PTR. PMID 21506190 · doi:10.1002/ptr.3506
- 2011. Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial Cancer. PMID 21287538 · doi:10.1002/cncr.25945
- 2010. In vivo enhancement of natural killer cell activity through tea fortified with Ayurvedic herbs Phytotherapy research : PTR. PMID 19504465 · doi:10.1002/ptr.2889
- 2009. The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis Journal of medicinal food. PMID 19857081 · doi:10.1089/jmf.2008.0244
- 2008. A prospective, randomized, controlled study to evaluate the efficacy and tolerability of Ayurvedic formulation "varuna and banana stem" in the management of urinary stones Journal of alternative and complementary medicine (New York, N.Y.). PMID 19040391 · doi:10.1089/acm.2008.0189
- 2008. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial Journal of alternative and complementary medicine (New York, N.Y.). PMID 18611150 · doi:10.1089/acm.2008.0018
- 2007. Effects of soluble fiber (Plantago ovata husk) on plasma lipids, lipoproteins, and apolipoproteins in men with ischemic heart disease The American journal of clinical nutrition. PMID 17413119 · doi:10.1093/ajcn/85.4.1157
- 2006. Bulk agent Plantago ovata after Milligan-Morgan hemorrhoidectomy with Ligasure Phytotherapy research : PTR. PMID 16708408 · doi:10.1002/ptr.1926
- 2006. Phoenix sylvestris Roxb pollen allergy: a 2-year randomized controlled trial and follow-up study of immunotherapy in patients with seasonal allergy in an agricultural area of West Bengal, India Journal of investigational allergology & clinical immunology. PMID 17153886
- 2005. Role of Terminalia arjuna in ischaemic mitral regurgitation International journal of cardiology. PMID 15837100 · doi:10.1016/j.ijcard.2004.10.045
- 2004. Evaluation of the effects of East Indian sandalwood oil and alpha-santalol on humans after transdermal absorption Planta medica. PMID 14765284 · doi:10.1055/s-2004-815446
- 2003. Effect of bitter melon (Momordica charantia Linn) on level and function of natural killer cells in cervical cancer patients with radiotherapy Journal of the Medical Association of Thailand = Chotmaihet thangphaet. PMID 12678140
- 2001. Microcirculatory effects of total triterpenic fraction of Centella asiatica in chronic venous hypertension: measurement by laser Doppler, TcPO2-CO2, and leg volumetry Angiology. PMID 11666123
- 1996. Picrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent--experimental & clinical studies Journal of postgraduate medicine. PMID 9715310
- 1995. Salutary effect of Terminalia Arjuna in patients with severe refractory heart failure International journal of cardiology. PMID 7649665 · doi:10.1016/0167-5273(95)02320-v
- 1994. Digestibility and bulking effect of ispaghula husks in healthy humans Gut. PMID 7829013 · doi:10.1136/gut.35.12.1747
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