Jatyadi Taila
Jatyadi Taila is a classical Ayurvedic taila, a medicated oil. Listed in Ayurvedic Formulary of India (AFI). Sushruta Samhita (Chikitsa Sthana) and Ashtanga Hridayam. One of the premier Vrana Ropana (wound healing) formulations in Ayurveda. The Ayurvedic Formulary of India (Part I, entry 8:17) lists 20 ingredients, beginning with Jati, Nimba, Patola and Naktamala.
| Also known as | Jatyadi Taila, JatyadiTaila |
|---|---|
| Pharmacopoeia status | Listed in Ayurvedic Formulary of India (AFI). Referenced in Sushruta Samhita, Ashtanga Hridayam, and Bhaishajya Ratnavali. HPTLC standardization markers (beta-sitosterol, lupeol, karanjin) have been established for quality control. Manufactured under GMP standards. |
Composition
As given in the Ayurvedic Formulary of India, Part I, entry 8:17 (JATYADI TAILA), which cites Sarngadharasamhita, Madhyamakhanda, Adhyaya 9; 168-170.. Names, parts and quantities are transcribed as printed and checked row by row against the book. Manufacturers' versions of a classical formulation can differ from the formulary.
| # | Ingredient | Part | Quantity |
|---|---|---|---|
| 1 | Jati * | leaf | 10.66 g. |
| 2 | Nimba | leaf | 10.66 g. |
| 3 | Patola | Lf. / Pl. | 10.66 g. |
| 4 | Naktamala (karanja) | leaf | 10.66 g. |
| 5 | Siktha (madhicchista) | 10.66 g. | |
| 6 | Madhuka (yasti) | root | 10.66 g. |
| 7 | Kustha | root | 10.66 g. |
| 8 | Haridra | rhizome | 10.66 g. |
| 9 | Daruharidra | stem | 10.66 g. |
| 10 | Katurohini (katuka) | rhizome | 10.66 g. |
| 11 | Manjistha | stem | 10.66 g. |
| 12 | Padmaka | heart wood | 10.66 g. |
| 13 | Lodhra | stem bark | 10.66 g. |
| 14 | Abhaya (haritaki) | pericarp | 10.66 g. |
| 15 | Nilotpala (utpala) * | flower | 10.66 g. |
| 16 | Tutthaka (tuttha) | 10.66 g. | |
| 17 | Sariva (sveta sariva) | root | 10.66 g. |
| 18 | Naktamala (karanja) | seed | 10.66 g. |
| 19 | Taila (tila) | oil | 768 g. |
| 20 | Water | 211 |
* The scanned text was damaged at this row and the name was read from the entry's own Sanskrit verse.
The evidence at a glance
6papers on this site for this drug, published 2011 to 2026, every one with a DOI.
- 1Other clinical studies and reviews
- 5Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Jatyadi Taila |
Where is it described in the classical texts?
Sushruta Samhita (Chikitsa Sthana) and Ashtanga Hridayam. One of the premier Vrana Ropana (wound healing) formulations in Ayurveda. Contains 16 medicinally important plants. Also referenced in Bhaishajya Ratnavali.
How does it work?
- Curcumin from Turmeric promotes wound healing by upregulating TGF-beta and VEGF expression, enhancing collagen deposition, angiogenesis, and re-epithelialization
- Nimbidin and azadirachtin from Neem are reported to have broad-spectrum antimicrobial activity
- Karanjin (identified by HPTLC) from Karanja provides anti-inflammatory and antimicrobial effects specifically targeting wound-colonizing bacteria
- Beta-sitosterol and lupeol (identified by HPTLC) provide anti-inflammatory action and stimulate fibroblast proliferation, accelerating granulation tissue formation
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Chronic wounds and venous ulcers: traditionally used for chronic wounds and venous ulcers. A clinical study reported faster reduction in wound area compared with povidone-iodine dressings.
- Burn wounds: traditionally used for burn wounds. Animal studies have reported increased collagen deposition and epithelialization in excision wound models.
- Fissure-in-ano (anal fissures): traditionally used for anal fissure wounds. Clinical studies have reported faster wound repair when it was used alongside Ksharasutra therapy.
What do recent studies show?
- Shailajan S, Menon S, Pednekar S and others 2011. Wound healing efficacy of Jatyadi Taila: in vivo evaluation in rat using excision wound model. Journal of ethnopharmacology. PMID 21907784 · doi:10.1016/j.jep.2011.08.050
Published in Journal of Ethnopharmacology/PubMed, the study demonstrated significant wound healing acceleration in rats, with enhanced collagen deposition, epithelialization, and wound contraction compared to control groups. - Prasannan D, Shindhe PS, Jadar PG and others 2023. Efficacy of Jatyadi, Madhughrita and honey tulle in wound management: a three-arm randomized controlled clinical trial. Journal of Ayurveda and integrative medicine. PMID 37271064 · doi:10.1016/j.jaim.2023.100719
Published in PMC, this three-arm randomized controlled trial compared Jatyadi Taila, Madhughrita and honey tulle dressings in wound management. - Chavan SV, Guha S, Raza K and others 2025. QbD Optimized Nanoemulsion Based Topical Formulation of Jatyadi Taila: Unveiling its In Vitro and In Vivo Efficacy for Enhanced Wound Healing. Pharmaceutical research. PMID 41350969 · doi:10.1007/s11095-025-03929-w
Published in Pharmaceutical Research (Springer), a nanoemulsion formulation of JT showed enhanced in vitro fibroblast proliferation and migration, with improved in vivo wound healing in full-thickness wound-bearing Wistar rats.
Recent safety updates
- Non-irritant on skin (confirmed in preclinical safety evaluation on rabbit skin). Well-tolerated for topical wound application. In vitro studies confirm antimicrobial activity without cytotoxicity to human fibroblasts at therapeutic concentrations.
- Not for internal consumption. Avoid on deep puncture wounds or severely infected wounds requiring surgical intervention. Large multicenter trials and pharmacokinetic studies of topical absorption are still needed for complete safety characterization. Formulation parameter standardization is an ongoing area of research.
Dosage forms and preparation
Dosage Forms: Taila (medicated oil for topical application), Spray (modern), Gel (modern)
Standard Dosage: Topical application on wounds, ulcers, fistula, sufficient quantity 1-2 times daily. The Ayurvedic Formulary of India attributes this formula to Sarngadharasamhita, Madhyamakhanda, Adhyaya 9; 168-170.
Optimal Timing: After wound cleaning with Triphala kwath, 1-2 times daily
Storage: Store in amber glass bottles in a cool, dry place. Temperature not exceeding 25°C. Enhanced microbial controls for wound-care product.
Marker Compounds: Berberine, Azadirachtin, Curcumin, Karanjin, Sesamin, Jasmone
Vehicle (Anupana): Not applicable, topical use only. For Nadivrana: soak cotton wick (pichu) and insert.
Synergistic Combinations
- Jatyadi Ghrita (ghee variant)
- Triphala Kwath (wound wash)
- Kaishore Guggulu (internal)
- Gandhaka Rasayana (internal)
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Other clinical studies and reviews1
- 2026. Interstitial cystitis with Hunner's ulcers managed with Jatyadi Taila Uttarabasti - A case seriesJournal of Ayurveda and integrative medicine. PMID 42497785 · doi:10.1016/j.jaim.2026.101358
Laboratory and animal studies5
- 2025. QbD Optimized Nanoemulsion Based Topical Formulation of Jatyadi Taila: Unveiling its In Vitro and In Vivo Efficacy for Enhanced Wound HealingPharmaceutical research. PMID 41350969 · doi:10.1007/s11095-025-03929-w
- 2023. Efficacy of Jatyadi, Madhughrita and honey tulle in wound management: a three-arm randomized controlled clinical trialJournal of Ayurveda and integrative medicine. PMID 37271064 · doi:10.1016/j.jaim.2023.100719
- 2011. Wound healing efficacy of Jatyadi Taila: in vivo evaluation in rat using excision wound modelJournal of ethnopharmacology. PMID 21907784 · doi:10.1016/j.jep.2011.08.050
- 2021. Topical application of Jatyadi Ghrita and Jatyadi Taila accelerates wound healing in Sprague-Dawley rats: a study in gamma-radiation-induced skin wound modelInternational journal of radiation biology. PMID 33872127 · doi:10.1080/09553002.2021.1913526
- 2023. Development and Validation of a Green Stability-Indicating HPTLC Method for Estimation of Curcumin, Gallic Acid, and Ursolic Acid From Polyherbal Formulation Jatyadi TailaJournal of AOAC International. PMID 36440895 · doi:10.1093/jaoacint/qsac147
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
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