Patola
Patola is a substance used in the Ayurvedic materia medica. It is described as Tikta (bitter) in taste, Laghu and Ruksha in quality, Ushna in potency and Katu in post-digestive effect.
The evidence at a glance
1paper on this site for this drug, every one with a DOI.
- 1Other clinical studies and reviews
A count is not a conclusion and a tier is a study design, not a verdict. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Patola |
Ayurvedic pharmacology (Dravyaguna)
| Property | Value | Description |
|---|---|---|
| Rasa (Taste) | Tikta | Primary taste |
| Guna (Quality) | Laghu, Ruksha | Physical quality |
| Virya (Potency) | Ushna | Heating/Cooling effect |
| Vipaka (Post-digestive) | Katu | Post-digestive effect |
Dosage forms and preparation
Dosage Forms: Swarasa (fresh juice), Kwatha (decoction), Churna (powder), Capsule, Tablet, Cooked vegetable preparation
Standard Dosage: 10-20 mL fresh juice daily; 3-5 g dried fruit/leaf powder daily; 15-30 mL decoction twice daily; 500 mg extract twice daily
Optimal Timing: Fresh juice or decoction: traditionally taken in the morning on an empty stomach. As food: cooked preparation with meals. Extract supplements: after meals.
Storage: Fresh fruit: 5-10 deg C, ventilated storage. Dried powder: airtight containers, below 25 deg C, RH <55%. Extracts: amber containers, cool and dry.
Marker Compounds: Cucurbitacin B, Cucurbitacin E, Beta-sitosterol, Stigmasterol, Lupeol, Ursolic acid, Gallic acid
Synergistic Combinations
- Nimba (Tikta Rasa combination for blood purification)
- Guduchi (traditionally paired for liver support; see hepatoprotective)
- Haridra (anti-inflammatory and skin health)
- Kutaki (traditionally used for liver support)
- Karela/Bitter gourd (traditional bitter-vegetable combination)
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Other clinical studies and reviews1
- 2025. Exploring Trichosanthes dioica: A Comprehensive Study of Its Ethnomedical Uses, Phytochemistry, Pharmacology and ToxicityChemistry & biodiversity. PMID 40845282 · doi:10.1002/cbdv.202501188
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.