Khadiradi Vati
Khadiradi Vati is a classical Ayurvedic vati, a herbal tablet or pill. Listed in Ayurvedic Formulary of India (AFI) Part I. The Ayurvedic Formulary of India (Part I, entry 12:6) lists 40 ingredients, beginning with Khadira sara, Arimeda, Candana and Padmaka.
| Also known as | Khadiradi Vati, KhadiradiVati |
|---|---|
| Pharmacopoeia status | Listed in Ayurvedic Formulary of India (AFI) Part I; Acacia catechu individually monographed in Ayurvedic Pharmacopoeia of India (API) Part I and Indian Pharmacopoeia; quality standards established by CCRAS for Khadiradi Vati preparations |
Composition
As given in the Ayurvedic Formulary of India, Part I, entry 12:6 (KHADIRADI GUTIKA (MUKHAROGA)), which cites Carakasamhita, Cikitsasthana, Adhyaya 26; 206-210½.. Names, parts and quantities are transcribed as printed and checked row by row against the book. Manufacturers' versions of a classical formulation can differ from the formulary.
| # | Ingredient | Part | Quantity |
|---|---|---|---|
| 1 | Khadira sara (khadira) * | heart wood | 4.800 kg. |
| 2 | Arimeda (vitkhadira) | stem bark | 9.600 kg. |
| 3 | Water for decoction * | 49.152 l., reduced to 12.288 l. | |
| 4 | Candana (sveta candana) | heart wood | 12 g. |
| 5 | Padmaka | heart wood | 12 g. |
| 6 | Usira | root | 12 g. |
| 7 | Manjistha * | stem | 12 g. |
| 8 | Dhataki * | flower | 12 g. |
| 9 | Ghana (musta) * | rhizome | 12 g. |
| 10 | Prapaundarika * | 12 g. | |
| 11 | Yastyahva (yasti) | root | 12 g. |
| 12 | Tvak | stem bark | 12 g. |
| 13 | Ela (suksmaila) | seed | 12 g. |
| 14 | Padma (kamala) * | flower | 12 g. |
| 15 | Kesara (naga kesara) | stamens | 12 g. |
| 16 | Laksa | 12 g. | |
| 17 | Rasanjana (daruharidra) * | St. Ext. | 12 g. |
| 18 | Mamsi (jata mamsi) * | Rz./Rt. | 12 g. |
| 19 | Haritaki | pericarp | 12 g. |
| 20 | Bibhitaka | pericarp | 12 g. |
| 21 | Amalaki | pericarp | 12 g. |
| 22 | Lodhra * | stem bark | 12 g. |
| 23 | Balaka (hrivera) * | root | 12 g. |
| 24 | Haridra * | rhizome | 12 g. |
| 25 | Daru haridra | stem | 12 g. |
| 26 | Phalini (priyangu) | flower | 12 g. |
| 27 | Ela (suksmaila) | seed | 12 g. |
| 28 | Samanga (lajjalu) * | 12 g. | |
| 29 | Katphala | stem bark | 12 g. |
| 30 | Vaca | 12 g. | |
| 31 | Yavasa (yavasaka) | whole plant | 12 g. |
| 32 | Agaru | heart wood | 12 g. |
| 33 | Pattanga | root | 12 g. |
| 34 | Gairika * | 12 g. | |
| 35 | Anjana (srotanjana) | 12 g. | |
| 36 | Lavanga | flower bud | 48 g. |
| 37 | Nakha (vyaghranakha) | fruit | 48 g. |
| 38 | Kakkola (kankola) | fruit | 48 g. |
| 39 | Jatikosa (jatiphala) | Ar. | 48 g. |
| 40 | Karpura | Sub. Ext. | 192 g. |
* The scanned text was damaged at this row and the name was read from the entry's own Sanskrit verse.
The Formulary gives the dose as 2 g, with anupana, the vehicle it is taken with, of honey. This is what the Formulary records for the classical preparation. It is not a dose for any product, and not advice to take anything.
The evidence at a glance
1paper on this site for this drug, every one with a DOI.
- 1Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people.true See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Khadiradi Vati |
Where is it described in the classical texts?
Sharangdhara Samhita (Madhyama Khanda); described in various Samhitas and classical texts for Mukha Roga (oral diseases); also referenced in Bhaishajya Ratnavali (Mukha Roga Chikitsa) and Yoga Ratnakara
How does it work?
- Oral antiseptic action: Khadira bark rich in catechins (flavonoids, catechin, catechuic acid, pyrocatechin, quercetin) provides astringent and antimicrobial action against oral pathogens including Streptococcus mutans
- Anti-inflammatory mucosal healing: Yashtimadhu (glycyrrhizin) soothes inflamed oral and pharyngeal mucosa with cooling Virya (Madhura Rasa), while Kankola and Lavanga reduce local inflammation
- Bioavailability enhancement: Pippali (piperine) boosts bioavailability of active compounds and warms channels through Ushna Virya, clearing stagnation in respiratory and oral Srotas
- Astringent tissue tonification: Khadira’s Kashaya Rasa (astringent taste) is classically described as tightening gum tissue and supporting oral mucosal health
- Antimicrobial and deodorant: Camphor (Kapoor) and Lavanga (eugenol) are traditionally used as antimicrobial and deodorant agents for halitosis
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Traditionally used for oral health (tonsillitis, gingivitis, stomatitis, mouth ulcers). In vitro studies have reported antimicrobial activity against Streptococcus and E. coli.
- Traditionally used for cough and sore throat. A clinical study reported improvement in cough scores.
- Traditionally used for halitosis (foul breath). The formulation includes camphor, clove, and cardamom.
- Traditionally used for voice clarity and hoarseness. The formulation includes Yashtimadhu and Khadira.
What do recent studies show?
No study for this section could be traced to a published paper. Classical formulations are researched largely in journals that PubMed does not index, so an absence here reflects the reach of the index rather than the state of the evidence.
Recent safety updates
- Generally safe for oral use as a lozenge/dissolvable tablet; contains Gairika (red ochre mineral); avoid swallowing large quantities; not recommended for children under 5 years
- Camphor component contraindicated in very young children (risk of seizures); avoid in known allergy to any ingredient; long-term continuous use may cause oral dryness due to astringent action; pregnancy and lactation - use under guidance
Dosage forms and preparation
Dosage Forms: Vati (lozenge), Modern lozenges, Mouth-dissolving tablets (modern)
Standard Dosage: 2 g, as given in the Ayurvedic Formulary of India, Part I, entry 12:6. 1-2 tablets to be sucked slowly, 3-4 times daily. The page’s tablet count and this weight relate only through the mass of a tablet, which the formulary does not state. The formulary’s anupana: honey. The formulary attributes this formula to Carakasamhita, Cikitsasthana, Adhyaya 26; 206-210½.
Optimal Timing: As needed for Mukha roga (oral diseases), throat irritation, or after meals for oral hygiene
Storage: Store in airtight containers in a cool, dry place. Protect from moisture and heat. Temperature not exceeding 25°C. Individual wrapping recommended.
Marker Compounds: Catechin, Epicatechin, Camphor, Eugenol (from Lavanga), 1,8-Cineole (from Ela)
Vehicle (Anupana): Honey, per the formulary; tablets are sucked slowly in the mouth. Do not chew or swallow whole.
Synergistic Combinations
- Eladi Vati
- Irimedadi Taila
- Triphala Kwath (gargling)
- Dashana Samskara Churna
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Laboratory and animal studies1
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.