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Kaishore Guggul

Kaishore Guggul is a classical Ayurvedic guggulu, a resin-based preparation. Listed in Ayurvedic Formulary of India (AFI) Part I; monographed in Ayurvedic Pharmacopoeia of India (API); recognized by CCRAS (Central Council for Research in Ayurvedic Sciences). The Ayurvedic Formulary of India (Part I, entry 5:2) lists 17 ingredients, beginning with Guggulu-suddha, Haritaki, Bibhitaka and Amalaki.

Key facts
Also known asKaishore Guggul, KaishoreGuggul
Pharmacopoeia statusListed in Ayurvedic Formulary of India (AFI) Part I; monographed in Ayurvedic Pharmacopoeia of India (API); recognized by CCRAS (Central Council for Research in Ayurvedic Sciences)

Composition

As given in the Ayurvedic Formulary of India, Part I, entry 5:2 (KAISORA GUGGULU), which cites Bhaisajyaratnavali, Vataraktadhikara; 97-101.. Names, parts and quantities are transcribed as printed and checked row by row against the book. Manufacturers' versions of a classical formulation can differ from the formulary.

#IngredientPartQuantity
1Guggulu-suddhaexudate768 g
2Haritakipericarp256 g
3Bibhitakapericarp256 g
4Amalakipericarp256 g
5Chinnaruha (guduci (printed "gudtici", OCR of guduci)) *stem1.536 kg
6Water for decoction12.288 l. reduced to 6.144 l.
7Haritaki *pericarp8 g
8Bibhitaka *pericarp8 g
9Amalakipericarp8 g
10Sunthirhizome24 g
11Maricafruit24 g
12Pippali *fruit24 g
13Krmiripu (vidanga)fruit24 g
14Trivrtroot12 g
15Dantiroot12 g
16Amrta (guduci (printed "gudiici")) *stem48 g
17Ghrta (goghrta) *384 g

* The scanned text was damaged at this row and the name was read from the entry's own Sanskrit verse.

The Formulary gives the dose as 3 g, with anupana, the vehicle it is taken with, of Mudga yusa,milk,sugandhijala. This is what the Formulary records for the classical preparation. It is not a dose for any product, and not advice to take anything.

Source scan of the formulary

The evidence at a glance

2papers on this site for this drug, published 2010 to 2019, every one with a DOI.

  • 1Other clinical studies and reviews
  • 1Laboratory and animal studies

A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.

Names and identification

LanguageName
EnglishKaishore Guggul

Where is it described in the classical texts?

Sharangdhara Samhita (Madhyama Khanda, Chapter 7); also referenced in Bhaishajya Ratnavali (Vatarakta Chikitsa)

How does it work?

  • Uric acid reduction: Guggulsterones have been proposed to promote renal excretion of uric acid by modulating renal tubular transporters (URAT1, GLUT9)
  • Anti-inflammatory cascade: Guduchi (Tinospora cordifolia) contains berberine and tinosporaside that inhibit NF-kB signaling and suppress TNF-alpha, IL-1beta, and IL-6 production
  • Antioxidant defense: Triphala and Guduchi polyphenols scavenge reactive oxygen species, protecting joint cartilage from oxidative degradation
  • Blood purification (Rakta Shodhana): Combined action of Guduchi and Triphala has been proposed to act by enhancing hepatic conjugation pathways and promoting elimination of metabolic waste
  • Bioavailability enhancement: Trikatu (especially piperine from Maricha and Pippali) enhances intestinal absorption and inhibits P-glycoprotein efflux, increasing systemic availability of active compounds

Which traditional uses are supported by research?

These summaries come from the source notes, which do not name the studies behind them.

  • Vatarakta (gout): traditionally used in classical practice for gout. A clinical case series reported reductions in uric acid levels and joint inflammation.
  • Traditionally used for blood purification and skin diseases. Pharmacological studies have reported antioxidant and anti-inflammatory activity.
  • Animal studies have reported anti-inflammatory and analgesic activity, including inhibition of carrageenan-induced paw edema.
  • Ama Pachana (detoxification): traditionally used for detoxification. Clinical observations have reported improved hepatic function and metabolic waste elimination.

What do recent studies show?

No study for this section could be traced to a published paper. Classical formulations are researched largely in journals that PubMed does not index, so an absence here reflects the reach of the index rather than the state of the evidence.

Recent safety updates

  • Generally considered safe under practitioner supervision; possible side effects include mild digestive discomfort and gastric upset; may lower blood sugar and blood pressure, requiring monitoring in diabetic and hypotensive patients
  • Contraindicated during pregnancy; not recommended for children below 5 years; patients with bleeding disorders should use cautiously as guggul may slow blood clotting; avoid concurrent use with anticoagulant medications

Dosage forms and preparation

Dosage Forms: Guggulu (resinous pill/tablet), Modern compressed tablet, Capsule (modern)

Standard Dosage: 250-500 mg twice or thrice daily with warm water. The Ayurvedic Formulary of India, Part I, entry 5:2 states a dose of 3 g; this is higher than the figure above, and the two are recorded here as differing sources. The formulary’s anupana: Mudga yusa,milk,sugandhijala. The formulary attributes this formula to Bhaisajyaratnavali, Vataraktadhikara; 97-101.

Optimal Timing: After meals, twice or thrice daily, for Vatarakta (gout), Kushtha (skin diseases), and inflammatory conditions

Storage: Store in airtight containers in a cool, dry place. Temperature not exceeding 30°C.

Marker Compounds: Z-Guggulsterone, E-Guggulsterone, Berberine (from Guduchi), Piperine, Gallic acid, Embelin (from Vidanga)

Vehicle (Anupana): Warm water or Guduchi kwath (this differs from the formulary’s anupana given above)

Synergistic Combinations

What manufacturers publish about this preparation

Disclosure first. This site is published by Age Ayurveda, which sells Ayurvedic products, though not this preparation. Every cell states what that company's own product page carried when it was read, not our judgement of it. There is no score, no rank and no winner here, and the table is in alphabetical order for that reason.

The formulary entry above fixes the ingredients and the quantity of each. Whether you can check a particular product against it depends on what its manufacturer publishes. Of the 5 companies surveyed that sell a product under this name, this is what their pages carried when they were read on 8 October 2026.

CompanyWhat its product page publishes
BaidyanathNeither an ingredient list nor quantities
Maharishi AyurvedaNeither an ingredient list nor quantities
Patanjali AyurvedAn ingredient list, without quantities
Shree DhootapapeshwarIngredients and the quantity of each
Sitaram AyurvedaAn ingredient list, without quantities

This measures what each company publishes, not the quality of anything it makes. A company that publishes nothing here may make an excellent preparation, and the label in the box is a separate, regulated surface that is not what was read. What disclosure changes is whether a reader, a pharmacist or an answer engine can check a product against the formulary entry it claims.

Method, the full counts across every company surveyed, and what this measurement got wrong the first time: which manufacturers publish what is in the bottle. The URL of every page read is recorded in brand-disclosure.json. If a row here is wrong, including where the correction favours a company other than ours, tell us and we will fix it and say that we did. How the same companies' stated doses compare with the formulary dose, preparation by preparation: Ayurvedic company doses against the Ayurvedic Formulary of India.

Published research

Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.

Laboratory and animal studies1

  1. Ramachandran AP, Prasad SM, Prasad UN and others. 2010. A comparative study of Kaishora Guggulu and Amrita Guggulu in the management of Utthana VataraktaAyu. PMID 22048531 · doi:10.4103/0974-8520.82027

Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.

Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.

Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.