Krimighna Vati
Krimighna Vati is a classical Ayurvedic vati, a herbal tablet or pill. The Ayurvedic Formulary of India has no entry under this name.
| Also known as | Krimighna Vati, KrimighnaVati |
|---|---|
| Pharmacopoeia status | No entry under this name in the Ayurvedic Formulary of India; Krimighna Gana (antiparasitic group) recognized in all major Samhitas; Vidanga (Embelia ribes) individually monographed in Ayurvedic Pharmacopoeia of India (API) Part I; Azadirachta indica in API and Indian Pharmacopoeia |
Names and identification
| Language | Name |
|---|---|
| English | Krimighna Vati |
Key Ingredients
- Vidanga (Embelia ribes) fruit
- Neem (Azadirachta indica) leaf/bark
- Haridra (Curcuma longa - Turmeric) rhizome
- Pippali (Piper longum)
- Haritaki (Terminalia chebula)
- Vacha (Acorus calamus)
- Kampillaka (Mallotus philippensis)
Where is it described in the classical texts?
Charaka Samhita (Vimana Sthana, Chapter 7 - Krimighna Gana/Dashemani); also referenced in Sushruta Samhita, Ashtanga Hridayam (Krimighna Gana group of 10 antiparasitic herbs), and Bhaishajya Ratnavali
How does it work?
- Parasitic membrane disruption: Vidanga’s embelin (a benzoquinone) is held to impair parasitic cell membranes by interfering with mitochondrial electron transport chain, causing parasite death
- Growth inhibition: Neem’s azadirachtin disrupts parasitic growth by interfering with ecdysone-mediated molting cycle, preventing larval development and reproduction
- Anti-inflammatory gut support: Haridra (curcumin) has shown anti-inflammatory and antimicrobial effects in studies
- Digestive fire enhancement: Pippali and Vacha are classically held to enhance Agni (digestive fire), making the gut less hospitable to parasites
- Ama mobilization: Haritaki gently mobilizes Ama (toxic residue) from the gut while Pippali amplifies absorption through enhanced Srota (channel) penetration
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Traditionally used as an anthelmintic. A case study reported activity against a Hymenolepis nana tapeworm infection.
- Traditionally used for broad-spectrum antiparasitic action. Studies have reported membrane-disrupting and growth-inhibiting activity of Vidanga and Neem.
- Traditionally used to restore intestinal health. Studies have reported anti-inflammatory and antimicrobial properties of curcumin (Haridra) in the gut mucosa.
- Kushtha/Krimi (parasitic skin conditions): traditionally used for parasitic skin conditions. Studies have reported antimicrobial activity of Neem and Haridra.
What do recent studies show?
No study for this section could be traced to a published paper. Classical formulations are researched largely in journals that PubMed does not index, so an absence here reflects the reach of the index rather than the state of the evidence.
Recent safety updates
- Generally safe at recommended doses for short-term antiparasitic courses; may cause mild GI discomfort or loose stools during parasite expulsion phase; avoid in pregnancy and lactation
- Kampillaka is a potent purgative - dose must be carefully controlled; not recommended for children under 5 years without physician guidance; should be followed by probiotic restoration after treatment course; confirm parasitic infection through stool examination before use
Dosage forms and preparation
Dosage Forms: Vati (tablet/pill), Modern compressed tablet, Capsule (modern)
Standard Dosage: 250-500 mg twice or thrice daily with warm water.
Optimal Timing: On empty stomach, morning (Abhukta kala), for 3-7 days course. Follow with mild purgative (Eranda Taila or Triphala) to expel worms.
Storage: Store in airtight containers in a cool, dry place. Temperature not exceeding 30°C.
Marker Compounds: Embelin, Rottlerin (from Kampillaka)
Vehicle (Anupana): Warm water or buttermilk. Some texts recommend with jaggery for pediatric use.
Synergistic Combinations
- Vidangarishta
- Krimikuthara Rasa
- Palasha Kwath
- Triphala Churna (as adjuvant laxative)
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
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