Trivanga Bhasma
Trivanga Bhasma is a bhasma, a mineral or metal preparation reduced to ash by repeated calcination. However, lead toxicity risk undermines clinical applicability.
| Substance type | Mineral or metal preparation, not a plant |
|---|---|
| Also known as | Trivanga Bhasma, TrivangaBhasma |
The evidence at a glance
2papers on this site for this drug, published 2013 to 2014, 1 with a DOI.
- 1Other clinical studies and reviews
- 1Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Trivanga Bhasma |
Key Phytochemical Constituents
- Lead oxide/sulfide (~31.67% lead content)
- Tin oxide (~38.36% tin content)
- Zinc oxide (~17.1% zinc content)
- Sulfur compounds from Gandhaka processing
- Herbal organic residues from trituration media
How does it work?
These are proposed mechanisms; none is established in humans.
- Anti-diabetic action through combined zinc-mediated insulin sensitivity enhancement and pancreatic beta-cell support, with synergistic effects from trimetallic composition
- Urinary system regulation through diuretic and anti-lithiatic effects of combined metals, traditionally linked to Prameha (urinary disorders)
- Reproductive system support through tin (Vanga) mediated spermatogenesis enhancement and zinc-dependent reproductive hormone regulation
- Metabolic regulation through multi-metal enzyme cofactor provision affecting carbohydrate, lipid, and protein metabolism pathways
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Diabetes (Madhumeha): traditionally used for diabetes. Animal studies in STZ-induced diabetic rat models have reported reduced blood sugar. However, the risk of lead toxicity limits its clinical applicability.
- Urinary disorders (Mutra Roga): traditionally used for urinary disorders. No clinical study has separated its benefits from its toxicity.
- Infertility (Vandhyatva): traditionally used for infertility, with reproductive support attributed to the Vanga component. Its lead content makes this use particularly dangerous for reproductive health.
What do recent studies show?
- Jamadagni PS, Jamadagni SB, Singh R and others 2013. Repeated dose oral toxicity of Trivanga Bhasma in Swiss albino mice. Ayu. PMID 24049417 · doi:10.4103/0974-8520.115449
90-day study in Swiss albino mice at 7.8, 39.5 and 78 mg/kg (the therapeutic dose, 5x and 10x). No treatment-related effects at any dose; 78 mg/kg body weight, the highest dose tested, was set as the NOAEL. Normal cyto-architecture on histopathology of the high-dose group. - Rasheed A, Naik M, Mohammed-Haneefa KP and others 2014. Formulation, characterization and comparative evaluation of Trivanga bhasma: a herbo-mineral Indian traditional medicine. Pakistan journal of pharmaceutical sciences. PMID 25015442
Physicochemical characterization confirmed trimetallic composition. Comparative evaluation of preparations from different sources showed variations in metal content ratios.
Only studies that could be traced to a published paper are listed here. An absence here means we could not identify the source, not that no work exists.
Recent safety updates
- CONTAINS LEAD (31.67%): Despite Ayurvedic purification, lead content remains a serious safety concern. Lead has NO safe exposure level per modern toxicology.
- MOUSE REPEATED-DOSE STUDY: NOAEL of 78 mg/kg in mice, the highest dose tested (10x the therapeutic dose), with no treatment-related effects at any dose over 90 days.
- LEAD ACCUMULATION RISK: Chronic use may lead to cumulative lead exposure. Blood lead level monitoring essential for any patient taking this preparation.
- REGULATORY CONFLICT: While AYUSH permits its manufacture, FDA and WHO guidelines effectively prohibit lead-containing medicines. This creates a regulatory paradox.
What is it made of?
Mineral/Elemental Profile
- Primary component: Calcined mineral/metal oxide (after Shodhana and Marana)
- Particle size: Sub-micron to nanoparticle range
- Note: Exact composition depends on source material and preparation method
Dosage forms and preparation
Dosage Forms: Bhasma
Standard Dosage: 125–250 mg
Optimal Timing: With honey or Haridra (turmeric); before meals for Prameha
Storage: Airtight container; restricted drug storage
Marker Compounds: Lead oxide, Tin oxide, Zinc oxide
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Other clinical studies and reviews1
- 2014. Formulation, characterization and comparative evaluation of Trivanga bhasma: a herbo-mineral Indian traditional medicinePakistan journal of pharmaceutical sciences. PMID 25015442
Laboratory and animal studies1
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.