Patola Patra
Patola Patra is a substance used in the Ayurvedic materia medica. Chlorophyll-associated compounds require bile salt emulsification for absorption. Leaf saponins have better bioavailability than fruit saponins due to lower molecular weight profiles.
| Also known as | Patola Patra, PatolaPatra |
|---|
Names and identification
| Language | Name |
|---|---|
| English | Patola Patra |
Ayurvedic pharmacology (Dravyaguna)
| Property | Value | Description |
|---|---|---|
| Rasa (Taste) | Tikta | Primary taste |
| Guna (Quality) | Laghu, Ruksha | Physical quality |
| Virya (Potency) | Sheeta | Heating/Cooling effect |
| Vipaka (Post-digestive) | Katu | Post-digestive effect |
What is it made of?
Mineral/Elemental Profile
- Primary component: Mineral-derived preparation
- Note: Composition varies by specific preparation method
Analytical Methods: XRD, ICP-OES, SEM-EDS
Dosage forms and preparation
Dosage Forms: Swarasa (fresh leaf juice), Kwatha (decoction), Churna (leaf powder), Capsule, Tablet, Lepa (paste)
Standard Dosage: 10-15 mL fresh leaf juice daily; 2-4 g dried leaf powder daily; 15-20 mL decoction twice daily; 500 mg leaf extract twice daily
Bioavailability: Leaf-specific flavonoids (quercetin, kaempferol glycosides) from Trichosanthes dioica leaves show moderate bioavailability (15-30%). Chlorophyll-associated compounds require bile salt emulsification for absorption. Leaf saponins have better bioavailability than fruit saponins due to lower molecular weight profiles. Ascorbic acid from fresh leaves is rapidly absorbed (>80%).
Optimal Timing: Fresh juice: morning on empty stomach for blood purification. Decoction: between meals. Leaf powder supplements: after meals with warm water.
Standardized Extract: Patola leaf extract (10:1) standardized to total flavonoids >4% (as quercetin equivalents), total phenolics >8% GAE, and ascorbic acid >1% (in fresh preparations).
Shelf Life: Fresh leaves: 1-2 days refrigerated; Fresh juice: 4-6 hours; Dried leaf powder: 12-18 months; Extract: 18-24 months; Capsules: 24 months
Storage: Fresh leaves: refrigerated 5-10 deg C in perforated bags. Dried powder: airtight, below 25 deg C, RH <50%, protected from light (to preserve chlorophyll). Extracts: amber containers, below 25 deg C.
Marker Compounds: Quercetin, Kaempferol, Gallic acid, Chlorogenic acid, Ascorbic acid, Beta-carotene, Luteolin, Beta-sitosterol
Extraction Methods
- Fresh leaf juice extraction by mechanical pressing
- Aqueous decoction
- Hydroalcoholic extraction (50-60% ethanol)
- Shade-drying followed by powdering
- Methanol extraction for flavonoid profiling
Synergistic Combinations
- Nimba-Patra (leaf-based blood purification combination)
- Guduchi (hepatoprotective synergy)
- Bhringaraja Patra (liver tonic leaf combination)
- Haridra (Tikta Rasa anti-inflammatory formula)
- Kutaja (anti-diarrheal and bitter tonic)
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