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Bharangi

Clerodendrum serratum (L.) Moon

Bharangi (Clerodendrum serratum (L.) Moon) is a plant drug, from the Lamiaceae (formerly Verbenaceae) family. Included in Ayurvedic Pharmacopoeia of India; documented in regional WHO SEARO traditional medicine databases.

Key facts
Botanical nameClerodendrum serratum (L.) Moon
FamilyLamiaceae (formerly Verbenaceae) · other entries in this family
OrderLamiales
Pharmacopoeia statusIncluded in Ayurvedic Pharmacopoeia of India; documented in regional WHO SEARO traditional medicine databases
Taxon identifiersGBIF 8355397 · Wikidata Q10865838 · NCBI Taxonomy 1158923

The evidence at a glance

12papers on this site for this drug, published 2014 to 2026, every one with a DOI.

  • 1Systematic reviews and meta-analyses
  • 1Other clinical studies and reviews
  • 10Laboratory and animal studies

A count is not a conclusion and a tier is a study design, not a verdict. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.

Names and identification

LanguageName
EnglishBharangi
Latin/BotanicalClerodendrum serratum (L.) Moon

Key Phytochemical Constituents

How does it work?

  • Anti-asthmatic: Saponins and terpenoids are reported to inhibit mast cell degranulation, reduce IgE levels, and suppress Th2 cytokine (IL-4, IL-5, IL-13) production
  • Anti-inflammatory: Oleanolic acid and hispidulin are reported to inhibit 5-LOX and COX-2, reducing leukotriene and prostaglandin synthesis
  • Hepatoprotective: Acteoside and flavonoids are reported to scavenge hepatic free radicals and restore glutathione levels in damaged liver tissue

Which traditional uses are supported by research?

These summaries come from the source notes, which do not name the studies behind them.

  • Shwasa-Kasahara: traditionally used for asthma. Animal studies using an ovalbumin-induced asthma model have reported reduced bronchial inflammation and IgE.
  • Traditionally used as an anti-inflammatory for joint disorders. Animal studies have reported inhibition of carrageenan-induced edema.
  • Traditionally used to protect the liver. Animal studies in CCl4-induced hepatotoxicity models have reported normalization of liver enzymes.

What do recent studies show?

Only studies that could be traced to a published paper are listed here. An absence here means we could not identify the source, not that no work exists.

Recent safety updates

  • Acute oral toxicity studies reportedly found LD50 > 2000 mg/kg (UNSOURCED)
  • No significant drug interactions reported; however, patients on anti-asthmatic medications should use under medical supervision for potential synergistic effects

What is it made of?

Key Active Markers

  • Mannitol
  • Hispidulin
  • Acteoside (verbascoside)
  • Scutellarein
  • Spinasterol
  • Serratumin A
  • Oleanolic acid

Dosage forms and preparation

Dosage Forms: Churna (powder), Kashayam (decoction), Tablet, Capsule, Kwath Ghana (solid extract), Vati (traditional pill)

Standard Dosage: 3-6g powder twice daily; 50-100ml decoction; 500mg extract capsule; traditionally 1-3g with honey for respiratory conditions

Optimal Timing: Before meals with honey for respiratory conditions; with warm water for anti-inflammatory effects; twice daily for chronic conditions

Storage: Cool, dry place away from light. Airtight containers for powder. Tablets in blister packs to protect from moisture.

Marker Compounds: Hispidulin, Scutellarein-7-glucuronide, Bharangin (clerodane diterpene), Clerosterol, Beta-sitosterol, Ursolic acid, Oleanolic acid

Synergistic Combinations

  • Traditionally combined with Kantakari for respiratory conditions
  • Traditionally combined with Vasa (Adhatoda) for cough
  • Traditionally combined with Tulsi for the upper respiratory tract
  • With Pippali for enhanced bioavailability and Kapha reduction
  • With Haridra for anti-allergic formulations

Published research

Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.

Systematic reviews and meta-analyses1

  1. Gogoi B, Gogoi D, Silla Y and others. 2017. Network pharmacology-based virtual screening of natural products from Clerodendrum species for identification of novel anti-cancer therapeuticsMolecular bioSystems. PMID 28070575 · doi:10.1039/c6mb00807k

Other clinical studies and reviews1

  1. Patel JJ, Acharya SR, Acharya NS. 2014. Clerodendrum serratum (L.) Moon. - a review on traditional uses, phytochemistry and pharmacological activitiesJournal of ethnopharmacology. PMID 24727551 · doi:10.1016/j.jep.2014.03.071

Laboratory and animal studies10

  1. Suksanga A, Eawsakul K, Bunluepuech K. 2026. Preparation and Evaluation of Niosomal Clerodendrum serratum (Linn.) Moon Extract Formulations: Comparative In Silico and In Vitro Studies of Drying Methods for the Treatment of HemorrhoidsScientifica. PMID 42064586 · doi:10.1155/sci5/3662572
  2. Patel RR, Mishra A, Singh SK and others. 2025. Mechanistic evaluation of Clerodendrum serratum anti-biofilm potency against Mycobacterium speciesMicrobial pathogenesis. PMID 40812437 · doi:10.1016/j.micpath.2025.107985
  3. Vidyasagar, Patel RR, Singh SK and others. 2024. Facile green synthesis of silver nanoparticles derived from the medicinal plant Clerodendrum serratum and its biological activity against Mycobacterium speciesHeliyon. PMID 38799742 · doi:10.1016/j.heliyon.2024.e31116
  4. Hasan A, Devi Ms S, Sharma G and others. 2023. Vathasura Kudineer, an Andrographis based polyherbal formulation exhibits immunomodulation and inhibits chikungunya virus (CHIKV) under invitro conditionsJournal of ethnopharmacology. PMID 36181982 · doi:10.1016/j.jep.2022.115762
  5. Arora P, Ansari SH, Nainwal LM. 2022. Clerodendrum serratum extract attenuates production of inflammatory mediators in ovalbumin-induced asthma in ratsTurkish journal of chemistry. PMID 38143476 · doi:10.3906/kim-2107-22
  6. Tiwari RK, Chanda S, M U and others. 2021. Anti-Inflammatory and Anti-Arthritic Potential of Standardized Extract of Clerodendrum serratum (L.) MoonFrontiers in pharmacology. PMID 33912046 · doi:10.3389/fphar.2021.629607
  7. Mahajan H, Singh Arora D, Singh H and others. 2021. Scientific validation of the antimicrobial and antiproliferative potential of Clerodendrum serratum (L.) Moon, its phytoconstituents and their biosafety by acute oral toxicity studyDrug and chemical toxicology. PMID 31368375 · doi:10.1080/01480545.2019.1643875
  8. Vasudev S, More VS, Ananthraju KS and others. 2021. Potential of herbal cocktail of medicinal plant extracts against 'big four' snake venoms from IndiaJournal of Ayurveda and integrative medicine. PMID 34334287 · doi:10.1016/j.jaim.2021.04.006
  9. Joshi B, Panda SK, Jouneghani RS and others. 2020. Antibacterial, Antifungal, Antiviral, and Anthelmintic Activities of Medicinal Plants of Nepal Selected Based on Ethnobotanical EvidenceEvidence-based complementary and alternative medicine : eCAM. PMID 32382275 · doi:10.1155/2020/1043471
  10. Vazhayil BK, Rajagopal SS, Thangavelu T and others. 2017. Neuroprotective effect of Clerodendrum serratum Linn. leaves extract against acute restraint stress-induced depressive-like behavioral symptoms in adult miceIndian journal of pharmacology. PMID 28458420 · doi:10.4103/0253-7613.201028

Reference lists that include it

Oleanolic acid, Ursolic acid

Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.

Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.

Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.