Guloochyadi Kashayam
Guloochyadi Kashayam is a classical Ayurvedic kashaya, a water decoction. Listed in the Ayurvedic Formulary of India (AFI). Sharangdhara Samhita Madhyamakhanda 2/8; Astanga Hridayam. Also described in Sahasrayogam (circa 15th century CE southern compendium) under Jwara Chikitsa (fever treatment). The Ayurvedic Formulary of India (Part II, entry 4:6) lists 5 ingredients: Gudtci 1 Part, Dhanyaka 1 Part, Arista 1 Part, Rakta candana 1 Part and Padmaka 1 Part.
| Also known as | Guloochyadi Kashayam, GuloochyadiKashayam |
|---|---|
| Pharmacopoeia status | Listed in the Ayurvedic Formulary of India (AFI). Referenced in Sharangdhara Samhita and Sahasrayogam. Recognized by the Pharmacopoeia Commission for Indian Medicine & Homoeopathy (PCIM&H). |
Composition
As given in the Ayurvedic Formulary of India, Part II, entry 4:6 (GUDUCYADI GANA KVATHA CURNA), which cites Sarangadharasamhita, Madhyamakhanda, Adhydaya 2; 8%. Names, parts and quantities are transcribed as printed and checked row by row against the book. Manufacturers' versions of a classical formulation can differ from the formulary.
| # | Ingredient | Part | Quantity |
|---|---|---|---|
| 1 | Gudtci | stem | 1 Part |
| 2 | Dhanyaka | fruit | 1 Part |
| 3 | Arista (nimba) | stem bark | 1 Part |
| 4 | Rakta candana | Ht.wd. | 1 Part |
| 5 | Padmaka | stem | 1 Part |
The Formulary gives the dose as 48 g. This is what the Formulary records for the classical preparation. It is not a dose for any product, and not advice to take anything.
Names and identification
| Language | Name |
|---|---|
| English | Guloochyadi Kashayam |
Where is it described in the classical texts?
Sharangdhara Samhita Madhyamakhanda 2/8; Astanga Hridayam. Also described in Sahasrayogam (circa 15th century CE southern compendium) under Jwara Chikitsa (fever treatment).
How does it work?
- Immunomodulatory action through NK cell activation and enhanced non-specific immunity (Guduchi, Nimba)
- Anti-inflammatory activity via suppression of pro-inflammatory cytokines and reduction of CRP levels
- Antipyretic action through multiple pathways including prostaglandin synthesis inhibition
- Antioxidant, antibacterial, antiviral, and antimalarial activities from the synergistic herb combination
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Fever of various etiologies: traditionally used for fever. Studies have reported immunomodulatory and antipyretic activity.
- Burning sensation (Daha): traditionally used for burning sensation. Raktachandana and Padmaka are described as cooling in classical practice.
- Loss of appetite and nausea during fever: traditionally used for these complaints. The formulation is described as having digestive and antiemetic properties.
- Infections with inflammatory component: traditionally used for these conditions. Studies have reported anti-inflammatory activity, including reduced CRP.
What do recent studies show?
No study for this section could be traced to a published paper. Classical formulations are researched largely in journals that PubMed does not index, so an absence here reflects the reach of the index rather than the state of the evidence.
Recent safety updates
- Generally well tolerated. No significant adverse effects reported in clinical trials. May cause mild gastrointestinal discomfort in sensitive individuals.
- Guduchi may lower blood sugar; diabetic patients on hypoglycemics should use with caution and monitor blood glucose levels. Neem (Nimba) should be used cautiously in pregnancy.
What is it made of?
The Ayurvedic Formulary of India recipe, every ingredient with its part and quantity, is in the composition table near the top of this page.
Dosage forms and preparation
Dosage Forms: Kashayam (decoction), Kashayam tablet (modern), Concentrated liquid (modern)
Standard Dosage: 15-30 mL or 2 tablets twice daily before meals. The Ayurvedic Formulary of India, Part II, entry 4:6 specifies 48 g of the kvatha curna to prepare the decoction, which is a quantity of drug rather than a dose taken, so it is not comparable with the volume above. The formulary attributes this formula to Sarngadharasamhita, Madhyamakhanda, Adhyaya 2; 8½.
Optimal Timing: Before meals, morning and evening, especially for Jwara (fever) and immunomodulation
Storage: Fresh: use same day. Concentrates: amber glass at room temperature. Tablets: airtight containers at room temperature.
Marker Compounds: Berberine, Tinosporaside, Columbin, Palmatine, Magnoflorine, Arabinogalactan (polysaccharide)
Vehicle (Anupana): Warm water (tablets); as is (liquid kashayam)
Synergistic Combinations
- Amritarishta
- Guduchi Satva
- Sudarshana Churna
- Panchanimba Churna
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.