Dhanyaka
Coriandrum sativum L.
Dhanyaka (Coriandrum sativum L.) is a plant used in Ayurveda, from the Apiaceae (Umbelliferae) family. Not individually listed in WHO monographs on selected medicinal plants; recognized in European, British, and Indian pharmacopoeias; GRAS status by FDA.
| Botanical name | Coriandrum sativum L. |
|---|---|
| Family | Apiaceae (Umbelliferae) · other entries in this family |
| Order | Apiales |
| Pharmacopoeia status | Not individually listed in WHO monographs on selected medicinal plants; recognized in European, British, and Indian pharmacopoeias; GRAS status by FDA |
| Taxon identifiers | GBIF 3034871 · Wikidata Q41611 · NCBI Taxonomy 4047 |
Names and identification
| Language | Name |
|---|---|
| English | Dhanyaka |
| Latin/Botanical | Coriandrum sativum L. |
Key Phytochemical Constituents
- Linalool (60-80% of seed essential oil - primary active)
- Gamma-terpinene
- Decanal
- Geranyl acetate
- Camphor
- Quercetin and rutin (flavonoids)
- Caffeic acid and chlorogenic acid (phenolics)
- Coumarins
- Tocopherols
- Fatty acids (petroselinic acid - unique)
How does it work?
- Anxiolytic and neuroprotective mechanism through linalool-mediated modulation of GABAergic neurotransmission and glutamate receptor inhibition, reducing neuronal excitotoxicity
- Hypoglycemic mechanism through stimulation of insulin secretion from pancreatic beta cells and enhancement of peripheral glucose uptake, mediated by flavonoid and essential oil fractions
- Antimicrobial mechanism through linalool disruption of bacterial cell membrane integrity and inhibition of efflux pump activity, showing broad-spectrum activity
Which traditional uses are supported by research?
- Digestive and carminative properties validated through clinical and preclinical studies, confirming Ayurvedic use as Deepana-Pachana in digestive disorders (Agnimandya)
- Anxiolytic properties validated through animal model studies showing dose-dependent reduction in anxiety markers, supporting traditional use as a cooling and calming herb
- Hypoglycemic activity validated through multiple in vivo and some clinical studies, confirming traditional use in Prameha (diabetes management)
What do recent clinical trials show?
- Chaurasia PK, Bharati SL 2025. Coriander: A holistic outlook on its chemistry and pharmacology. Food chemistry. PMID 39719783 · doi:10.1016/j.foodchem.2024.142444
Holistic review documenting the full phytochemical spectrum including essential oils, flavonoids, phenolic compounds, and fatty acids, with emphasis on pharmacological mechanisms and drug delivery advancements.
2 further claims previously listed here could not be traced to a published paper and have been removed. An absence here means we could not identify the source, not that no work exists.
Recent safety updates
- Widely consumed spice with GRAS status; generally safe at culinary and traditional therapeutic doses; rare cases of contact dermatitis and photosensitivity reported with fresh coriander leaf handling
- High-dose essential oil ingestion may cause hepatic or renal effects; potential interaction with antidiabetic medications due to hypoglycemic potential; contraindicated in known Apiaceae allergy
What is it made of?
Key Active Markers
- Linalool
- Decanal
- Camphor
- Quercetin
- Rutin
- Flavonoids
- Coumarins
- Tocopherols
Analytical Methods: HPLC fingerprinting, TLC (identity), LC-MS/MS (marker quantification)
Dosage forms and preparation
Dosage Forms: Churna (powder), Kashayam (decoction), Hima (cold infusion), Tablet, Capsule, Essential oil, Arka (distillate)
Standard Dosage: 3-6g seed powder twice daily; 50-100ml decoction or cold infusion twice daily; 500mg extract capsule twice daily; essential oil: 1-3 drops in carrier
Bioavailability: Coriandrum sativum seeds contain linalool (60-70% of essential oil), flavonoids, and coumarins. Linalool has good oral bioavailability (>60%) due to favorable lipophilicity and small molecular size. Flavonoid glycosides (rutin, quercetin-3-glucuronide) have moderate bioavailability (15-25%), improved by gut microbial deglycosylation. Cold infusion (Hima) preserves volatile constituents better than hot decoction. The traditional practice of light roasting (Bharjana) before use modifies volatile profile and may improve digestibility.
Optimal Timing: After meals as digestive aid; before meals for appetite stimulation; Hima (cold infusion) throughout the day for Pitta conditions and burning sensation
Standardized Extract: Essential oil: standardized to NLT 65% linalool by GC-MS. Seed extract: NLT 1% total flavonoids (as rutin). Extract ratio 5:1.
Shelf Life: 1 year (powder - due to volatile loss); 2 years (tablet/capsule); 3 years (essential oil in sealed amber bottle); whole seeds: 2-3 years
Storage: Whole seeds in airtight containers at room temperature. Powder: airtight, moisture-proof containers below 25 deg C - use quickly after grinding. Essential oil: amber glass, cool place, nitrogen headspace.
Marker Compounds: Linalool, Geraniol, Geranyl acetate, Camphor, Rutin, Quercetin, Coumarins
Extraction Methods
- Steam distillation for essential oil (Dhanyaka Taila)
- Cold infusion (Hima - traditional)
- Aqueous decoction
- Hydroalcoholic extraction (50:50)
- Supercritical CO2 for high-quality essential oil
Synergistic Combinations
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Other clinical studies and reviews10
- 2025. Coriander: A holistic outlook on its chemistry and pharmacologyFood chemistry. PMID 39719783 · doi:10.1016/j.foodchem.2024.142444
- 2023. Coriandrum sativum and Its Utility in Psychiatric DisordersMolecules (Basel, Switzerland). PMID 37513187 · doi:10.3390/molecules28145314
- 2023. Coriander (Coriandrum sativum) Polyphenols and Their Nutraceutical Value against Obesity and Metabolic SyndromeMolecules (Basel, Switzerland). PMID 37241925 · doi:10.3390/molecules28104187
- 2022. Ethnobotanical and phytochemical aspects of the edible herb Coriandrum sativum LJournal of food science. PMID 35279837 · doi:10.1111/1750-3841.16085
- 2021. Plants Used as AntihypertensiveNatural products and bioprospecting. PMID 33174095 · doi:10.1007/s13659-020-00281-x
- 2021. Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A reviewAvicenna journal of phytomedicine. PMID 34745916 · doi:10.22038/AJP.2021.55681.2786
- 2021. Coriandrum sativum L.: A Review on Ethnopharmacology, Phytochemistry, and Cardiovascular BenefitsMolecules (Basel, Switzerland). PMID 35011441 · doi:10.3390/molecules27010209
- 2019. Phytochemical and bioactive profile of Coriandrum sativum LFood chemistry. PMID 30827604 · doi:10.1016/j.foodchem.2019.01.171
- 2015. Coriander (Coriandrum sativum L.) and its bioactive constituentsFitoterapia. PMID 25776008 · doi:10.1016/j.fitote.2015.03.012
- 2006. Coriander PMID 30000851
Laboratory and animal studies2
- 2024. Coriander (Coriandrum sativum L.) from Alentejo (South Portugal)-Ethnobotany and Potential Industrial UseFoods (Basel, Switzerland). PMID 38540919 · doi:10.3390/foods13060929
- 2024. Genome-wide mining and characterization of MATE transporters in Coriandrum sativum LMolecular biology research communications. PMID 38915458 · doi:10.22099/mbrc.2024.49840.1954
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