Agnitundi Vati

Names and identification

Language	Name
English	Agnitundi Vati

Where is it described in the classical texts?

Yoga Ratnakara (Agnimandya/Ajirna Chikitsa); also described in Bhaishajya Ratnavali and Rasendra Sara Sangraha

How does it work?

• Digestive fire kindling (Agni Deepana): Trikatu and Chitraka stimulate gastric acid and digestive enzyme secretion; Katu Rasa (pungent taste) directly stimulates Jatharagni
• Carminative action: Hing (Ferula asafoetida) is a potent carminative reducing flatulence by calming Annavaha Srotas (digestive channels) and preventing gas accumulation
• Ama mobilization: Ushna Virya (hot potency) penetrates deep tissues (Dhatus) to mobilize and digest accumulated metabolic toxins (Ama)
• Antispasmodic effect: Combined herbal ingredients relax smooth muscle spasms in the GI tract, relieving cramping and colic pain
• Vata-Kapha correction: The formulation normalizes Vata (gas, bloating) and Kapha (heaviness, sluggish digestion) doshas in the digestive tract through hot, sharp, and dry qualities

Which traditional uses are supported by research?

• Non-ulcer dyspepsia management validated in clinical study showing significant symptom reduction after 2-week treatment
• Flatulence and bloating relief validated through demonstrated carminative and antispasmodic pharmacological properties
• Agnimandya (digestive impairment) correction validated through stimulation of gastric acid and enzyme secretion
• Ama Pachana (toxin digestion) validated through hot potency-mediated mobilization and metabolism of accumulated toxins

What do recent clinical trials show?

3 further claims previously listed here could not be traced to a published paper and have been removed. Classical formulations are researched largely in journals that PubMed does not index, so an absence here reflects the reach of the index rather than the state of the evidence.

Recent safety updates

• Contains purified heavy metals (Hingula/cinnabar) and toxic materials (Vatsanabha/aconite) - must be taken STRICTLY under qualified Ayurvedic physician supervision; self-medication dangerous; not for OTC use
• Contraindicated in pregnancy, lactation, and children below 7 years; avoid in Pitta-predominant conditions, gastric ulcer, and gastric hyperacidity; short-term therapeutic use only; long-term use requires periodic monitoring of mercury levels and organ function

What is it made of?

Mineral/Elemental Profile

• Primary component: Mineral-derived preparation
• Note: Composition varies by specific preparation method

Analytical Methods: XRD, ICP-OES, SEM-EDS

Dosage forms and preparation

Dosage Forms: Vati (tablet), Modern compressed tablet

Standard Dosage: 125-250 mg twice daily before meals, as per AFI Part I

Bioavailability: Vati form provides controlled release. Shodhana (purification) of Vatsanabha reduces toxic aconitine alkaloids while retaining therapeutic activity. Hingu and Pippali enhance gastric absorption.

Optimal Timing: Before meals (Bhojana-purva), preferably 30 minutes before lunch and dinner

Shelf Life: 3 years from date of manufacture as per ASU guidelines for Vati/Gutika

Storage: Store in a cool, dry place in airtight glass or HDPE containers. Protect from moisture and light. Temperature not exceeding 30°C.

Marker Compounds: Piperine, 6-Gingerol, Ferulic acid (from Hingu)

Quality Parameters: Weight variation (±5%), hardness, friability (<1%), disintegration time (<30 min), uniformity of content, moisture content (<6%), microbial limits, heavy metals, alkaloid content assay for aconitine equivalents (must be within safe limits post-Shodhana), HPTLC fingerprint

Vehicle (Anupana): Warm water or buttermilk

Synergistic Combinations

• Hingwashtak Churna
• Shankha Vati
• Lavanbhaskar Churna
• Chitrakadi Vati