Tapyadi Loha
Tapyadi Loha is a compound loha formulation of bhasmas (mineral or metal preparations reduced to ash by repeated calcination) and herbs, given as Vati. Listed in Ayurveda Sara Sangraha; recognized as a classical Ayurvedic formulation under the Drugs and Cosmetics Act, 1940; manufactured by licensed pharmacies under AYUSH guidelines.
| Substance type | Mineral or metal preparation, not a plant |
|---|---|
| Also known as | Tapyadi Loha, TapyadiLoha |
| Pharmacopoeia status | Listed in Ayurveda Sara Sangraha; recognized as a classical Ayurvedic formulation under the Drugs and Cosmetics Act, 1940; manufactured by licensed pharmacies under AYUSH guidelines |
The evidence at a glance
1paper on this site for this drug, every one with a DOI.
- 1Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people.true See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Tapyadi Loha |
Where is it described in the classical texts?
Ayurveda Sara Sangraha (Ayurved Saar Sangrah); also referenced in classical Rasashastra texts
How does it work?
- Triple iron source (Loha Bhasma + Mandura Bhasma + Swarnamakshik Bhasma) provides several iron-bearing ingredients, traditionally used in Pandu (anemia)
- Raupya Bhasma (silver calx) has antimicrobial and Pitta-pacifying properties, supporting liver detoxification pathways
- Shilajit is traditionally regarded as a bioenhancer and contains fulvic acid
- Daruharidra (Berberis aristata) contains berberine, providing hepatoprotective and cholagogue effects supporting liver and biliary function
- Trikatu enhances bioavailability and digestive fire (Agni deepana) for optimal nutrient assimilation
- Triphala provides antioxidant protection, gentle bowel regulation, and vitamin C for iron absorption
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Pandu (anemia) and Kamla (jaundice-like conditions): traditionally used for these conditions in classical practice.
- Liver and spleen disorders (Yakrit-Pliha Roga): traditionally used for these conditions. Ingredients include Daruharidra (berberine), Shilajit, and Triphala. A toxicity study reported no liver toxicity.
What do recent studies show?
- Hinge PH, Tambe MS, Murudkar PH and others 2024. Acute and subacute oral toxicity evaluation of Ayurvedic formulation Tapyadi loha in rats. Drug and chemical toxicology. PMID 39165010 · doi:10.1080/01480545.2024.2389965
Tapyadi Loha showed no mortality or signs of toxicity at single oral dose of 2000 mg/kg; 28-day repeated dose at 1000 mg/kg showed no behavioral, hematological, biochemical, or histopathological abnormalities in rats at the tested doses
Only studies that could be traced to a published paper are listed here. An absence here means we could not identify the source, not that no work exists.
Recent safety updates
- 2024 toxicity study observed no toxicity in rats at a single dose of 2000 mg/kg and a 28-day repeated dose of 1000 mg/kg
- Contains multiple iron sources (Loha + Mandura + Swarnamakshik) - higher cumulative iron intake requires careful monitoring of serum ferritin and iron studies
- Raupya Bhasma (silver) content requires verification of proper preparation (Shodhana) and heavy metal testing per API standards
- Contraindicated in hemochromatosis, iron overload conditions, active liver disease (despite hepatoprotective herbs), and during pregnancy without supervision
- Should be used under strict medical supervision with regular LFT and KFT monitoring; recommended treatment duration should not be exceeded
What is it made of?
Mineral/Elemental Profile
- Primary component: Mineral-derived preparation
- Note: Composition varies by specific preparation method
Dosage forms and preparation
Dosage Forms: Vati
Standard Dosage: 125–250 mg twice daily
Optimal Timing: After meals with honey
Storage: Airtight container
Marker Compounds: Iron oxide, Multiple herbal compounds
Vehicle (Anupana): Honey, Guduchi Swarasa, or Triphala Kwatha
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Laboratory and animal studies1
- 2024. Acute and subacute oral toxicity evaluation of Ayurvedic formulation Tapyadi loha in ratsDrug and chemical toxicology. PMID 39165010 · doi:10.1080/01480545.2024.2389965
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.