Mandura Bhasma
Mandura Bhasma is a bhasma, a mineral or metal preparation reduced to ash by repeated calcination.
| Substance type | Mineral or metal preparation, not a plant |
|---|---|
| Also known as | Mandura Bhasma, ManduraBhasma |
The evidence at a glance
1paper on this site for this drug, 0 with a DOI.
- 1Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people.true See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Mandura Bhasma |
Key Phytochemical Constituents
- Ferric oxide (Fe2O3) as primary constituent (~40-45% elemental iron)
- Magnetite (Fe3O4) phase
- Calcium, magnesium from processing media
- Silica and alumina traces
- Vitamin C and tannins from Amalaki (gooseberry) processing
How does it work?
- Hematopoietic iron supplementation through bioavailable iron oxide particles that support hemoglobin synthesis
- Hepatoprotective and spleen-supportive action through iron-mediated improvement of reticuloendothelial system function and blood filtration
- Deepana-Pachana (digestive enhancement) through iron-catalyzed metabolic enzyme activation and improvement of nutrient absorption
- Raktavardhaka (blood-building) action through combined iron supplementation and vitamin C (from Amalaki processing) synergy enhancing iron absorption
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Iron-deficiency anemia (Pandu Roga): traditionally used for this condition. Clinical studies have reported improvement in hemoglobin levels, with no adverse effects reported.
- Menstrual disorders (Raktapradar): traditionally used for this condition. A clinical study in women reported reduced menstrual blood loss.
- Liver and spleen enlargement (Yakrit-Pleeha Vikara): traditionally used for this condition. Preclinical studies have reported hepatoprotective activity and reticuloendothelial support.
What do recent studies show?
- Mulik SB, Jha CB 2011. Physicochemical characterization of an Iron based Indian traditional medicine: Mandura Bhasma. Ancient science of life. PMID 23284206
Iron oxide nanoparticles confirmed by XRD and SEM analysis. Particle size and iron oxide phases characterized, providing basis for standardization and quality control.
Only studies that could be traced to a published paper are listed here. An absence here means we could not identify the source, not that no work exists.
Recent safety updates
- SAFE AT 5X DOSE: No serious toxic effects at 55 mg/kg (5x therapeutic dose) for 60 days in rat studies
- CLINICAL SAFETY REPORTS: Clinical studies of the Punarnavadi Mandura formulation (not Mandura Bhasma alone) reported no adverse drug reactions or events
- IRON OVERLOAD MONITORING: Excessive or long-term use without monitoring may lead to elevated serum ferritin and oxidative stress. Periodic hemoglobin and ferritin checks advised.
- TOLERABILITY: Like Loha Bhasma, Mandura Bhasma is said in the source notes to cause fewer GI side effects than conventional iron supplements (UNSOURCED)
What is it made of?
Mineral/Elemental Profile
- Iron oxide (Fe2O3): Major component (iron slag)
- Silicon (Si): Trace
- Manganese (Mn): Trace
- Calcium (Ca): Trace
Dosage forms and preparation
Dosage Forms: Bhasma
Standard Dosage: 250–500 mg twice daily
Optimal Timing: After meals with Triphala Kwatha or honey
Storage: Airtight container
Marker Compounds: Iron oxide (Fe2O3), Silica, Trace manganese and magnesium
Vehicle (Anupana): Triphala Kwatha, honey, or as Mandura Vataka formulation
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Laboratory and animal studies1
- 2011. Physicochemical characterization of an Iron based Indian traditional medicine: Mandura BhasmaAncient science of life. PMID 23284206
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.