Saireyaka
Barleria strigosa
Saireyaka (Barleria strigosa) is a plant used in Ayurveda. Lignans show enhanced absorption with lipid co-administration. First-pass metabolism is moderate; flavonoids undergo glucuronidation and sulfation in the intestinal wall. Churna and capsules: store below 25 deg C in airtight containers, protected from light and moisture.
| Botanical name | Barleria strigosa |
|---|---|
| Identity source | Ayurvedic Pharmacopoeia of India, Part I, Vol. V: NILAJHINTI (Root) |
| Also called | Barleria prionitis (attribution recorded without a cited source) Barleria cristata (reported in the literature) |
| Family | Acanthaceae · other entries in this family |
| Order | Lamiales |
| Taxon identifiers | GBIF 3770457 · Wikidata Q13893639 · NCBI Taxonomy 1749380 |
Names and identification
| Language | Name |
|---|---|
| English | Saireyaka |
Ayurvedic pharmacology (Dravyaguna)
| Property | Value | Description |
|---|---|---|
| Rasa (Taste) | Tikta, Madhura | Primary taste |
| Guna (Quality) | Snigdha | Physical quality |
| Virya (Potency) | Ushna | Heating/Cooling effect |
| Vipaka (Post-digestive) | Katu | Post-digestive effect |
Dosage forms and preparation
Dosage Forms: Kwatha (decoction), Churna (powder), Swarasa (fresh juice), Vati (tablet), Capsule, Taila (medicated oil)
Standard Dosage: 3-6 g churna per day in divided doses; 10-20 mL swarasa twice daily; 50-100 mL kwatha twice daily
Bioavailability: Moderate oral bioavailability for flavonoid and alkaloid constituents (25-40%). Lignans show enhanced absorption with lipid co-administration. First-pass metabolism is moderate; flavonoids undergo glucuronidation and sulfation in the intestinal wall.
Optimal Timing: Before meals for Raktapitta (bleeding disorders) indications; morning dose for general Pitta-pacifying action
Standardized Extract: Hydroalcoholic extract (8:1 DER), standardized to NLT 2.0% total flavonoids (as luteolin equivalents by UV spectrophotometry); aqueous extract for traditional kwatha preparations
Shelf Life: 12 months for swarasa (refrigerated with preservative); 24 months for churna; 36 months for standardized extract capsules
Storage: Swarasa: refrigerate at 2-8 deg C. Churna and capsules: store below 25 deg C in airtight containers, protected from light and moisture.
Marker Compounds: Luteolin, Apigenin, Beta-sitosterol, Lupeol, Quercetin glycosides
Extraction Methods
- Aqueous decoction
- Hydroalcoholic extraction (50-60% ethanol)
- Cold pressing for fresh juice (swarasa)
- Maceration in sesame oil for taila preparation
Synergistic Combinations
- Haridra (anti-inflammatory formulations for Raktapitta)
- Guduchi (immunomodulatory-antipyretic synergy)
- Sariva (blood purification formulations)
- Manjishtha (Pitta-related skin conditions)
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