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Pravala Pishti

Pravala Pishti is a pishti, a coral preparation ground fine without calcination; Pravala Bhasma is the separate calcined form.

Key facts
Substance typeMineral or metal preparation, not a plant
Also known asPravala Pishti, PravalaPishti

The evidence at a glance

12papers on this site for this drug, published 2002 to 2026, every one with a DOI.

  • 8Other clinical studies and reviews
  • 4Laboratory and animal studies

A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.

Names and identification

LanguageName
EnglishPravala Pishti

How does it work?

  • Calcium supplementation: CaCO3 from coral provides bioavailable calcium for bone mineralization
  • Acid-neutralizing antacid: Calcium carbonate neutralizes gastric HCl; traditionally used for hyperacidity
  • Pitta-pacifying and hemostatic: Described as cooling and traditionally used for Pitta-related bleeding disorders; calcium is essential for the coagulation cascade, supporting the traditional use in bleeding conditions

Which traditional uses are supported by research?

These summaries come from the source notes, which do not name the studies behind them.

  • Calcium deficiency and bone disorders: traditionally used for calcium deficiency and bone disorders. A preclinical study reported less bone loss linked to calcium and estrogen deficit. A multicenter clinical study in menopausal women reported on its safety.
  • Hyperacidity (Amlapitta) and bleeding disorders (Raktapitta): traditionally used as an antacid and for bleeding disorders. It contains calcium carbonate.

What do recent studies show?

Only studies that could be traced to a published paper are listed here. An absence here means we could not identify the source, not that no work exists.

Recent safety updates

  • GENERALLY SAFE: Like Mukta Pishti, Pravala Pishti is essentially a natural coral calcium supplement; heavy-metal content depends on sourcing and should be tested
  • Dose-dependent side effects: Excess intake (>2500 mg/day) can cause abdominal distension, flatulence, loss of appetite, and risk of kidney stone formation due to hypercalcemia
  • Environmental concern: Coral harvesting raises ecological sustainability questions; sourcing from sustainable or cultivated coral stocks is recommended
  • Quality control: Marine-derived products should be tested for marine pollutants, microbiological contamination, and heavy metal residues; GMP-certified sourcing essential

What is it made of?

Mineral/Elemental Profile

  • Primary component: Calcium carbonate (coral), not calcined
  • Particle size: Sub-micron to nanoparticle range
  • Note: Exact composition depends on source material and preparation method

Dosage forms and preparation

Dosage Forms: Pishti, Bhasma (Pravala Bhasma also available)

Standard Dosage: 250–500 mg twice daily

Optimal Timing: With honey or Malai; with meals for calcium supplementation

Storage: Airtight, dry container

Marker Compounds: Calcium carbonate (85–90%), Magnesium (2–3%), Strontium, Iron, Trace elements (70+ from marine origin)

Vehicle (Anupana): Honey, Gulkand, Malai, or pomegranate juice

Published research

Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.

Other clinical studies and reviews8

  1. Lin LC, Liu ZY, Yang JJ and others. 2024. Lipid metabolism reprogramming in cardiac fibrosisTrends in endocrinology and metabolism: TEM. PMID 37949734 · doi:10.1016/j.tem.2023.10.004
  2. Batiha GE, Al-Snafi AE, Thuwaini MM and others. 2023. Morus alba: a comprehensive phytochemical and pharmacological reviewNaunyn-Schmiedeberg's archives of pharmacology. PMID 36877269 · doi:10.1007/s00210-023-02434-4
  3. Kehrenberg MCA, Bachmann HS. 2022. Diuretics: a contemporary pharmacological classification?Naunyn-Schmiedeberg's archives of pharmacology. PMID 35294605 · doi:10.1007/s00210-022-02228-0
  4. Makhija EP, Espinosa-Hoyos D, Jagielska A and others. 2020. Mechanical regulation of oligodendrocyte biologyNeuroscience letters. PMID 31838017 · doi:10.1016/j.neulet.2019.134673
  5. Rondal JA. 2020. Down syndrome: A curative prospect?AIMS neuroscience. PMID 32607419 · doi:10.3934/Neuroscience.2020012
  6. Claes C, Lafetá AP. 2014. Proliferative vitreoretinopathyDevelopments in ophthalmology. PMID 25196769 · doi:10.1159/000360466
  7. Reddy PN, Lakshmana M, Udupa UV. 2003. Effect of Praval bhasma (Coral calx), a natural source of rich calcium on bone mineralization in ratsPharmacological research. PMID 14527824 · doi:10.1016/s1043-6618(03)00224-x
  8. Swynghedauw B. 2002. Myocardial remodelling: pharmacological targetsExpert opinion on investigational drugs. PMID 11996647 · doi:10.1517/13543784.11.5.661

Laboratory and animal studies4

  1. Yamashita K, Kinoshita FL, Yoshida SY and others. 2026. A whole-brain single-cell atlas of circadian neural activity in miceScience (New York, N.Y.). PMID 41231968 · doi:10.1126/science.aea3381
  2. Li X, Sun Y, Zhou Z and others. 2024. Deep Learning-Driven Exploration of Pyrroloquinoline Quinone Neuroprotective Activity in Alzheimer's DiseaseAdvanced science (Weinheim, Baden-Wurttemberg, Germany). PMID 38454653 · doi:10.1002/advs.202308970
  3. Someko H, Kataoka Y, Obara T. 2023. Drug fever: a narrative reviewAnnals of clinical epidemiology. PMID 38504950 · doi:10.37737/ace.23013
  4. Andrew R, Izzo AA. 2017. Principles of pharmacological research of nutraceuticalsBritish journal of pharmacology. PMID 28500635 · doi:10.1111/bph.13779

Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.

Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.

Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.