Morning Glory
Morning Glory is a substance used in the Ayurvedic materia medica. CAUTION: Some species contain lysergic acid amide (LSA). Bioavailability: Ergoline alkaloids (LSA, ergine) in seeds have high oral bioavailability (~40-60%) with rapid CNS penetration - this is a SAFETY concern.
| Also known as | Morning Glory, MorningGlory |
|---|
Names and identification
| Language | Name |
|---|---|
| English | Morning_Glory |
What is it made of?
Key Active Markers
- Derived from constituent herbs (see individual herb profiles)
- Standardized on primary bioactive markers
Analytical Methods: HPLC fingerprinting, TLC (identity), LC-MS/MS (marker quantification)
Dosage forms and preparation
Dosage Forms: Churna (seed powder, micro-dosed), Kwatha (leaf/root decoction), Capsules (standardized extract), Topical paste, Taila (medicated oil)
Standard Dosage: Seeds: NOT recommended for internal use due to ergot alkaloid content. Leaf/Root: 3-5 g powder per day; 50-100 mL decoction of leaves twice daily; topical as directed. CAUTION: Some species contain lysergic acid amide (LSA).
Bioavailability: Ergoline alkaloids (LSA, ergine) in seeds have high oral bioavailability (~40-60%) with rapid CNS penetration - this is a SAFETY concern. Leaf and root preparations contain different phytochemistry with flavonoids and glycoresins showing moderate absorption. Purgative glycoresins act locally on intestinal mucosa.
Optimal Timing: Morning on empty stomach for purgative action (under medical supervision); topical application as needed; specific timing per Virechana Panchakarma protocol
Standardized Extract: Leaf extract (8:1 aqueous) free from ergoline alkaloids (verified by LC-MS). Root extract standardized to 3-5% glycoresins for controlled purgative action. Certificate of analysis must confirm absence of LSA/ergine.
Shelf Life: Dried leaf/root powder: 18 months. Capsules: 24 months. Topical preparations: 18 months.
Storage: Store below 25 deg C in airtight containers. Protect from light and moisture. Restricted access storage for raw seed material (if held for research). All finished products labeled with appropriate warnings.
Marker Compounds: Glycoresins (turpethinic acids, if I. turpethum), Scopoletin, Umbelliferone, Kaempferol, Caffeic acid, LSA/Ergine (MUST be absent in formulations)
Extraction Methods
- Aqueous decoction of leaves/roots (safer parts)
- Hydroalcoholic extraction (50% ethanol)
- Leaf juice expression
- Oil infusion for topical preparations
Synergistic Combinations
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