Danti Moola
Baliospermum solanifolium
Danti Moola (Baliospermum solanifolium) is a plant used in Ayurveda. Must be used under qualified practitioner supervision. Bioavailability: Root contains higher concentration of diterpene esters than stem. Purgative principles act locally in the intestine with limited systemic absorption desired.
| Botanical name | Baliospermum solanifolium |
|---|---|
| Family | Euphorbiaceae · other entries in this family |
| Order | Malpighiales |
| Also known as | Danti Moola, DantiMoola |
| Taxon identifiers | GBIF 3062296 · Wikidata Q15386102 · NCBI Taxonomy 1962698 |
Names and identification
| Language | Name |
|---|---|
| English | Danti Moola |
Ayurvedic pharmacology (Dravyaguna)
| Property | Value | Description |
|---|---|---|
| Rasa (Taste) | Katu | Primary taste |
| Guna (Quality) | Tikshna, Laghu | Physical quality |
| Virya (Potency) | Ushna | Heating/Cooling effect |
| Vipaka (Post-digestive) | Katu | Post-digestive effect |
Dosage forms and preparation
Dosage Forms: Churna (powder) - Shodhita only, Kashayam (decoction), Tablet, Kwath Ghana (solid decoction extract)
Standard Dosage: 1-2g Shodhita root powder as purgative; 500mg-1g for mild laxative; 30-50ml decoction. Must be used under qualified practitioner supervision.
Bioavailability: Root contains higher concentration of diterpene esters than stem. Purgative principles act locally in the intestine with limited systemic absorption desired. Post-Shodhana processing in cow’s milk denatures protein-bound toxins and reduces phorbol ester load by 60-80%. Bioavailability of therapeutic laxative principles is adequate via oral route without enhancement.
Optimal Timing: Early morning on empty stomach with warm water; recommended only during Virechana therapy under Ayurvedic supervision
Standardized Extract: Shodhita root powder or aqueous extract. No standardized extract commercially available. Must carry certificate of Shodhana completion with batch records.
Shelf Life: 1 year (Shodhita powder in moisture-proof container); 2 years (tablet)
Storage: Airtight, light-resistant containers below 25 deg C and below 45% RH. Must be labeled ‘Shodhita Danti Moola - for use under medical supervision only.’ Store separately from general herbs.
Marker Compounds: Phorbol-12,13-didecanoate (toxicity marker - must be below specified limit post-Shodhana), Montanin, Beta-sitosterol, Jatrophenone
Extraction Methods
- Shodhana in cow’s milk (mandatory pre-processing)
- Aqueous decoction of Shodhita root
- Sequential extraction: first defatting with hexane, then hydroalcoholic (50:50)
- Traditional Kwath preparation
Synergistic Combinations
- With Trivrit for Virechana (therapeutic purgation) in Panchakarma
- With Triphala for balanced laxative formulation
- With Saindhava Lavana (rock salt) to improve palatability and reduce griping
- With Draksha (raisin) decoction as Anupana to soften purgative action
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Laboratory and animal studies4
- 2025. Protective effect of antioxidant triterpenes of Baliospermum solanifolium (burm.) suresh leaf extract against peroxidative cellular toxicityNatural product research. PMID 41396965 · doi:10.1080/14786419.2025.2602910
- 2024. Structurally diverse diterpenoids and phenanthrene derivatives from the roots of BaliospermumsolanifoliumPhytochemistry. PMID 38897264 · doi:10.1016/j.phytochem.2024.114194
- 2024. Anti-inflammatory effects of the Thai herbal remedy Yataprasen and biflavonoids isolated from Putranjiva roxburghii in RAW264.7 macrophagesJournal of ethnopharmacology. PMID 38442805 · doi:10.1016/j.jep.2024.117997
- 2024. Baliosperoid A attenuates lipopolysaccharide-induced acute lung injury by targeting SHP2 to inhibit inflammation and oxidative stressBioorganic chemistry. PMID 39577153 · doi:10.1016/j.bioorg.2024.107982
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