Age Ayurveda Nighantu

Vyaghri Haritaki

Vyaghri Haritaki is a compound formulation of several ingredients, from the Polyherbal Avaleha (confection) - classical Ayurvedic compound formulation family. Not listed in WHO monographs; recognized in Ayurvedic Pharmacopoeia of India and Ayurvedic Formulary of India; Kantakari (individual ingredient) is a well-documented Ayurvedic herb.

Key facts
Substance typeCompound formulation of several ingredients, not a single plant
FamilyPolyherbal Avaleha (confection) - classical Ayurvedic compound formulation
Also known asPolyherbal formulation: Solanum surattense Burm.f. (Kantakari/Vyaghri) + Terminalia chebula Retz. (Haritaki) as principal herbs, Vyaghri Haritaki, VyaghriHaritaki
Pharmacopoeia statusNot listed in WHO monographs; recognized in Ayurvedic Pharmacopoeia of India and Ayurvedic Formulary of India; Kantakari (individual ingredient) is a well-documented Ayurvedic herb

Names and identification

LanguageName
EnglishVyaghri Haritaki
Latin/BotanicalPolyherbal formulation: Solanum surattense Burm.f. (Kantakari/Vyaghri) + Terminalia chebula Retz. (Haritaki) as principal herbs

Key Phytochemical Constituents

How does it work?

  • Antitussive and bronchodilatory mechanism through Kantakari steroidal alkaloids relaxing bronchial smooth muscle and reducing cough reflex sensitivity, combined with Haritaki’s mucolytic action
  • Anti-inflammatory and anti-allergic mechanism through solasonine and tannin-mediated inhibition of mast cell degranulation and reduction of histamine release in airways
  • Mild laxative and detoxification mechanism through Haritaki’s chebulinic acid stimulating gentle peristalsis and binding toxins in the GI tract

Which traditional uses are supported by research?

  • Antitussive and anti-asthmatic efficacy validated through pharmacological studies confirming bronchodilatory and cough-suppressant properties, supporting premier use in Kasa (cough) and Shwasa (asthma)
  • Treatment of Pratishyaya (chronic rhinitis/sinusitis) supported by anti-inflammatory and antimicrobial properties of constituent herbs
  • Mild laxative and detoxification role validated through Haritaki’s well-established purgative pharmacology, confirming traditional use in maintaining digestive health

What do recent clinical trials show?

3 further claims previously listed here could not be traced to a published paper and have been removed. An absence here means we could not identify the source, not that no work exists.

Recent safety updates

  • Traditional avaleha preparation considered safe at recommended doses (5-10g with honey or warm water); Kantakari’s steroidal alkaloids are buffered by the jaggery/honey matrix of the confection
  • Solanine-containing herbs should be used cautiously during pregnancy; long-term safety data from controlled clinical trials is lacking; recommended to use under Ayurvedic practitioner supervision

What is it made of?

Mineral/Elemental Profile

  • Primary component: Mineral-derived preparation
  • Note: Composition varies by specific preparation method

Analytical Methods: XRD, ICP-OES, SEM-EDS

Dosage forms and preparation

Dosage Forms: Avaleha (confection/lehyam), Churna (powder blend), Capsule, Tablet

Standard Dosage: 5-10 g Avaleha twice daily with warm water or milk; 3-5 g churna twice daily; 500 mg-1 g extract capsule twice daily

Bioavailability: This is a polyherbal formulation combining Kantakari (Solanum surattense) with Haritaki (Terminalia chebula). Solasodine (from Kantakari) has moderate oral bioavailability (~25-35%). Chebulagic acid and gallic acid (from Haritaki) are absorbed as described in Haritaki/Triphala profiles. The Avaleha (jaggery/sugar-based confection) matrix serves as a taste-masking and slow-release vehicle. Ghee and honey used as processing adjuncts enhance bioavailability of both hydrophilic and lipophilic components.

Optimal Timing: After meals with warm water or milk; morning and evening; at bedtime for nocturnal cough/asthma

Standardized Extract: Avaleha as per AFI (Ayurvedic Formulary of India) specifications; individual herb extracts: Kantakari >0.5% solasodine, Haritaki >3% gallic acid by HPLC

Shelf Life: Avaleha: 18-24 months; Churna blend: 12-18 months; Capsules/Tablets: 24-36 months

Storage: Avaleha in wide-mouth glass or food-grade plastic jars at 15-25 deg C. Do not refrigerate (crystallization of sugar). Use dry, clean spoon for dispensing. Capsules in standard pharmaceutical packaging.

Marker Compounds: Solasodine (from Kantakari), Solanine (from Kantakari), Chebulagic acid (from Haritaki), Gallic acid (from Haritaki), Ellagic acid (from Haritaki), Piperine (from Pippali adjunct), Carpesterol

Extraction Methods

  • Traditional Avaleha Kalpana: decoction of Kantakari + Haritaki concentrated and processed with jaggery, honey, ghee, and spices (Pippali, Twak, Ela, Tamalpatra, Nagakesara)
  • Powdering and blending of individual herbs
  • Hydroethanolic extraction for standardized capsule form

Synergistic Combinations

  • This IS a synergistic formulation: Kantakari (bronchodilator, expectorant) + Haritaki (mild laxative, Rasayana, respiratory tonic)
  • Enhanced with Pippali (bioenhancer, respiratory stimulant)
  • Chaturjata (Twak, Ela, Tamalpatra, Nagakesara) - aromatic and carminative blend within the formulation
  • Honey and ghee as Yogavahi (bioenhancers and vehicles)

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