Vajra Bhasma
Vajra Bhasma is a bhasma, a mineral or metal preparation reduced to ash by repeated calcination.
| Substance type | Mineral or metal preparation, not a plant |
|---|---|
| Also known as | Vajra Bhasma, VajraBhasma |
The evidence at a glance
1paper on this site for this drug, every one with a DOI.
- 1Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people.true See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Vajra Bhasma |
Key Phytochemical Constituents
- Nano-diamond particles (carbon nanostructures)
- Carbon in various allotropic forms post-calcination
- Trace silica and alumina from processing
- Organic compounds from rose water and aloe vera media
- Iron and other trace elements from crucible materials
How does it work?
- Anti-cancer activity through nanodiamond-mediated immunostimulation: activates natural killer cells, promotes tumor cell apoptosis, reduces angiogenesis, and inhibits metastatic spread
- Immunomodulatory action through enhancement of both innate and adaptive immune responses, increasing phagocytic activity and lymphocyte proliferation
- Rasayana (rejuvenation) effect through carbon nanostructure-mediated cellular repair and antioxidant activity, supporting tissue regeneration and longevity
- Tridosha balancing through multi-system regulatory effects on Vata (nervous), Pitta (metabolic), and Kapha (structural) functions
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Cancer and tumors (Arbuda): traditionally used for Arbuda in classical practice. Animal studies have reported reduced tumor volume, less metastasis, and longer survival in tumor-bearing animals.
- Immune deficiency: preclinical studies have reported immunomodulatory activity, including increased NK cell activity and lymphocyte proliferation.
- Tuberculosis (Rajayakshma): traditionally used for Rajayakshma in classical practice. Anti-inflammatory and immune-enhancing activity has been reported, but clinical research specific to TB is limited.
What do recent studies show?
- Paladhi A, Rej A, Sarkar D and others 2022. Nanoscale Diamond-Based Formulation as an Immunomodulator and Potential Therapeutic for Lymphoma. Frontiers in pharmacology. PMID 35444547 · doi:10.3389/fphar.2022.852065
Functional nanodiamond-based Heerak Bhasma demonstrated immunostimulation that significantly reduced tumor cell proliferation, induced apoptosis, reduced tumor volume, inhibited metastasis, and increased life span of tumor-bearing animals.
Only studies that could be traced to a published paper are listed here. An absence here means we could not identify the source, not that no work exists.
Recent safety updates
- Safety: toxicology studies in mice have reported no hepatotoxicity, nephrotoxicity, or genotoxicity at doses equivalent to those used in practice, for preparations made by validated methods.
- STABLE HEMATOLOGY: Hematological profiles remained stable in animal studies; histopathological examination showed no cellular inflammation or necrosis
- LIMITED HUMAN DATA: Clinical trials in humans are still limited; most safety data from animal models and pilot studies
- PREPARATION-DEPENDENT: Adverse reactions usually due to improperly prepared or contaminated formulations; may include gastric irritation, metallic taste, or rare hypersensitivity
- EXTREME COST: Very expensive preparation, limiting widespread use and also increasing adulteration/substitution risk in commercial products
What is it made of?
Dosage forms and preparation
Dosage Forms: Bhasma
Standard Dosage: 15–30 mg (rare and premium)
Storage: Airtight container; premium storage
Marker Compounds: Carbon nanostructures, Trace mineral matrix from Bhavana
Vehicle (Anupana): Honey, ghee, or gold bhasma combination
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Laboratory and animal studies1
- 2022. Nanoscale Diamond-Based Formulation as an Immunomodulator and Potential Therapeutic for LymphomaFrontiers in pharmacology. PMID 35444547 · doi:10.3389/fphar.2022.852065
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.