Satyanashi
Argemone mexicana
Satyanashi (Argemone mexicana) is a plant drug, also called Brahmadandi, Svarnaksiri and Satyanasi. Use cautiously: latex is toxic in large doses.
| Botanical name | Argemone mexicana |
|---|---|
| Family | Papaveraceae · other entries in this family |
| Order | Ranunculales |
| Taxon identifiers | GBIF 2888485 · Wikidata Q683404 · NCBI Taxonomy 54796 |
| Sanskrit | ब्रह्मदण्डी (brahmadaṇḍī), स्वर्णक्षीरी (svarṇakṣīrī) |
|---|---|
| Hindi | सत्यानाशी (satyānāśī), भरभांड (bharabhāṃḍa), भड़भाड़ (bhaṛabhāṛa), घमोई (ghamoī) |
| Tamil | குடியோட்டுப்பூண்டு, பிரம்மத் தண்டு |
Sources: Names of Plants in India compilation for Argemone mexicana (indiantreepix 'Names of Plants in India :: Argemone mexicana L.'), Hindi: भरभांड, घमोई (ghamoee), फिरंगी धतूरा, पीला धतूरा, सत्यानाशी, सियालकांटा, तिल्मखार.; Names of Plants in India, Argemone mexicana: the Hindi list gives भरभांड (bharbhand), with भड़भाड़ recorded as an alternate spelling of the same name.; eFloraofIndia / Names of Plants in India, Argemone mexicana, Sanskrit: ब्रह्मदण्डी (brahmadandi); eFloraofIndia / Names of Plants in India, Argemone mexicana, Sanskrit: ब्रह्मदण्डी, हेमदुग्ध, हेमशिखा, कान्चक्षीरी, कटुपर्णी, पीतदुग्धा, सृगालकण्टक, स्वर्णक्षीरी; eFloraofIndia / Names of Plants in India, Argemone mexicana, Tamil: எலியோட்டி, குருக்கு, குடிக்குச்சகுனி, குடியோட்டுப்பூண்டு, பிரம்மத் தண்டு; eFloraofIndia / Names of Plants in India, Argemone mexicana, Tamil: எலியோட்டி, குருக்கு, குடிக்குச்சகுனி, குடியோட்டுப்பூண்டு, பிரம்மத் தண்டு (piram-mat-tantu).; eFloraofIndia and Names of Plants in India, Argemone mexicana, Hindi: भरभांड (bharbhand); eFloraofIndia and Names of Plants in India, Argemone mexicana, Hindi: सत्यानाशी (satyanashi), alongside भरभांड, फिरंगी धतूरा, पीला धतूरा, सियालकांटा.. How we source.
The evidence at a glance
12papers on this site for this drug, published 2012 to 2026, every one with a DOI.
- 3Other clinical studies and reviews
- 9Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Satyanashi |
Ayurvedic pharmacology (Dravyaguna)
| Property | Value | Description |
|---|---|---|
| Rasa (Taste) | Tikta | Primary taste |
| Guna (Quality) | Laghu, Ruksha | Physical quality |
| Virya (Potency) | Ushna | Heating/Cooling effect |
| Vipaka (Post-digestive) | Katu | Post-digestive effect |
Dosage forms and preparation
Dosage Forms: Churna (powder), Kwatha (decoction), Swarasa (fresh juice), Taila (seed oil), Capsule, Lepa (external paste)
Standard Dosage: 1-3 g root/whole plant powder per day; 5-10 mL seed oil externally; 50-100 mL kwatha twice daily. Use cautiously, latex is toxic in large doses.
Optimal Timing: External applications: twice daily on affected areas. Internal use (where permitted): after meals under medical supervision
Storage: Store below 25 deg C. Seed oil in amber glass bottles, nitrogen-flushed. Keep away from food products to prevent accidental contamination. Clearly label as NOT FOR INTERNAL USE (for oil preparations).
Marker Compounds: Sanguinarine, Dihydrosanguinarine, Berberine, Protopine, Argemone oil (fatty acid profile: linoleic acid >55%)
Synergistic Combinations
- Haridra (antimicrobial-anti-inflammatory synergy for skin conditions)
- Neem (dermatological formulations)
- Karanja (external antimicrobial applications)
- Snuhi (latex-based formulations for warts, external only)
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Other clinical studies and reviews3
- 2026. Retrospection of Argemone mexicana and its Derived Analogs as a Futuristic Approach Exhibiting Anticancer PotentialMini reviews in medicinal chemistry. PMID 41863239 · doi:10.2174/0113895575417548251208235008
- 2025. An In-depth Review on Argemone mexicana in the Management of Liver Health and Liver CancerAnti-cancer agents in medicinal chemistry. PMID 39225208 · doi:10.2174/0118715206307964240821051756
- 2016. Berberine and Its Role in Chronic DiseaseAdvances in experimental medicine and biology. PMID 27671811 · doi:10.1007/978-3-319-41334-1_2
Laboratory and animal studies9
- 2024. Assessment of Anticancer Properties of Argemone mexicana L. and Berberine: A Comparative StudyPlants (Basel, Switzerland). PMID 38794444 · doi:10.3390/plants13101374
- 2024. Multi-modal neuroprotection of Argemone mexicana L. against Alzheimer's disease: In vitro and in silico studyHeliyon. PMID 39286063 · doi:10.1016/j.heliyon.2024.e37178
- 2023. Synthesis and biological evaluation of Argemone mexicana-inspired antimicrobialsBeilstein journal of organic chemistry. PMID 37799174 · doi:10.3762/bjoc.19.108
- 2023. Phytotoxicity of Extracts of Argemone mexicana and Crotalaria longirostrata on Tomato Seedling PhysiologyPlants (Basel, Switzerland). PMID 38005753 · doi:10.3390/plants12223856
- 2023. Analysis of Biochemical and Antimicrobial Properties of Bioactive Molecules of Argemone mexicanaMolecules (Basel, Switzerland). PMID 37298904 · doi:10.3390/molecules28114428
- 2021. Effect of Argemone mexicana on Local Edema and LPS-Induced NeuroinflammationChemistry & biodiversity. PMID 33527713 · doi:10.1002/cbdv.202000790
- 2021. Characterizing the cytotoxic effects and several antimicrobial phytocompounds of Argemone mexicanaPloS one. PMID 33826680 · doi:10.1371/journal.pone.0249704
- 2016. Antifungal and Anticancer Potential of Argemone mexicana LMedicines (Basel, Switzerland). PMID 28930138 · doi:10.3390/medicines3040028
- 2012. Alkaloids and flavonoids of Argemone mexicanaNatural product research. PMID 21722040 · doi:10.1080/14786419.2010.529809
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
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