Kshara Parpati
Kshara Parpati is a rasa preparation, a herbo-mineral formulation of the rasa shastra tradition. Mutrashmari (urinary calculi/kidney stones) - traditional use supported by comparative clinical study showing litholytic and diuretic efficacy Mutrakrichra (dysuria/painful urination) - traditional primary indication validated through pharmaceutical review and clinical practice observations
| Substance type | Herbo-mineral (rasa shastra) preparation, not a single plant |
|---|---|
| Also known as | Kshara Parpati, KsharaParpati |
| Pharmacopoeia status | Listed in Siddha Yoga Sangraha; recognized as a classical Ayurvedic Parpati Kalpana; included in Ayurvedic Formulary of India (AFI); classified under mineral preparations of the Drugs and Cosmetics Act, 1940 |
Names and identification
| Language | Name |
|---|---|
| English | Kshara Parpati |
Where is it described in the classical texts?
Siddha Yoga Sangraha, Ashmari Mutrakrichra Adhikara (Urinary Stones and Dysuria Chapter)
How does it work?
- Surya Kshara (potassium nitrate) acts as a potent alkalizing agent, increasing urinary pH to dissolve uric acid and calcium oxalate stones
- Diuretic action of potassium nitrate increases urine volume, flushing out small calculi and preventing new stone formation
- Sphatika (alum) has astringent and antiseptic properties, reducing urinary tract inflammation and infection
- Navasadara (ammonium chloride) has urine-acidifying properties at certain concentrations but in Parpati form acts synergistically as a balanced urinary modifier
- Antacid-like action in the GI tract alleviates dyspepsia and acid-related digestive disorders
- Parpati Kalpana (flake preparation) method ensures rapid dissolution and absorption in the GI tract
Which traditional uses are supported by research?
- Mutrashmari (urinary calculi/kidney stones) - traditional use supported by comparative clinical study showing litholytic and diuretic efficacy
- Mutrakrichra (dysuria/painful urination) - traditional primary indication validated through pharmaceutical review and clinical practice observations
What do recent clinical trials show?
2 further claims previously listed here could not be traced to a published paper and have been removed. An absence here means we could not identify the source, not that no work exists.
Recent safety updates
- This is a purely chemical/mineral formulation without iron - no iron overload risk
- Potassium nitrate (Surya Kshara) in high doses may cause methemoglobinemia; strict dose adherence essential (125-500 mg)
- Ammonium chloride may cause metabolic acidosis at high doses or in patients with renal impairment
- Heavy metal contamination is not a primary concern for this mineral-salt formulation, but quality testing should verify absence of contaminants
- Contraindicated in patients with hyperkalemia, severe renal impairment, and cardiac conditions sensitive to potassium levels
What is it made of?
Mineral/Elemental Profile
- Primary component: Mineral-derived preparation
- Note: Composition varies by specific preparation method
Analytical Methods: XRD, ICP-OES, SEM-EDS
Dosage forms and preparation
Dosage Forms: Parpati (flake form)
Standard Dosage: 125–250 mg twice daily
Bioavailability: Enhanced; Parpati form (thin flake) has increased surface area for absorption
Optimal Timing: With buttermilk (Takra) or rice water (Tandulodaka)
Standardized Extract: Kajjali melted with Kshara (alkaline substance) and poured on banana leaf
Shelf Life: Indefinite
Storage: Airtight, moisture-proof container
Marker Compounds: Mercury sulfide, Potassium/sodium carbonates (from Kshara), Sulfur
Quality Parameters: Thin flake formation, uniform thickness, standard Parpati tests, free mercury <1 ppm
Vehicle (Anupana): Buttermilk (Takra) — classical combination
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