Krimi Kuthar Rasa
Krimi Kuthar Rasa is a rasa preparation, a herbo-mineral formulation of the rasa shastra tradition. Classical Rasashastra formulation from Bhaishajya Ratnavali; Schedule E-1 restricted medicine requiring prescription; manufactured under strict AYUSH licensing; regulatory scrutiny due to mercury and aconite content.
| Substance type | Herbo-mineral (rasa shastra) preparation, not a single plant |
|---|---|
| Also known as | Krimi Kuthar Rasa, KrimiKutharRasa |
| Pharmacopoeia status | Classical Rasashastra formulation from Bhaishajya Ratnavali; Schedule E-1 restricted medicine requiring prescription; manufactured under strict AYUSH licensing; regulatory scrutiny due to mercury and aconite content |
The evidence at a glance
1paper on this site for this drug, every one with a DOI.
- 1Other clinical studies and reviews
A count is not a conclusion and a tier is a study design, not a verdict. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Krimi Kuthar Rasa |
Where is it described in the classical texts?
Bhaishajya Ratnavali, Krimi Rogadhikara (Parasitic Diseases Chapter); also referenced in Rasendra Sara Sangraha and Bhava Prakasha
How does it work?
- Parada (mercury) in Kajjali form (HgS) creates a hostile environment for intestinal parasites through its sharp, penetrating, and toxic properties at micro-doses
- Vidanga (Embelia ribes) contains embelin, a potent anthelmintic compound that paralyzes and expels intestinal worms
- Palash Beej (Butea monosperma seeds) contain butin and palasonin with established anthelmintic activity against tapeworms
- Indrayava (Holarrhena antidysenterica) has anti-amoebic and anti-dysenteric properties through conessine alkaloid content
- Shuddha Vatsanabha (purified aconite) in micro-doses is classically described as Ushna Virya (hot potency) and Vishagna (anti-toxic)
- Loha Bhasma is traditionally included to support blood building
- Karpura (camphor) has antiseptic and carminative properties aiding in intestinal environment restoration
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Intestinal parasites (Krimi Roga), including roundworms, tapeworms, and pinworms: traditionally used as the primary indication. Ingredients include Vidanga (embelin) and Palash seeds (palasonin), which are described as having anthelmintic activity.
- Digestive disorders associated with parasitic infection: traditionally used for this purpose. Ingredients include Indrayava, Ajamoda, and Karpura, which are described as having carminative, digestive, and anti-amoebic properties.
What do recent studies show?
- Saper RB, Phillips RS, Sehgal A and others 2008. Lead, mercury, and arsenic in US- and Indian-manufactured Ayurvedic medicines sold via the Internet. JAMA. PMID 18728265 · doi:10.1001/jama.300.8.915
One-fifth of Ayurvedic medicines purchased online contained detectable lead, mercury, or arsenic exceeding acceptable daily intake standards; relevant to mercury-containing formulations like Krimi Kuthar Rasa
Only studies that could be traced to a published paper are listed here. An absence here means we could not identify the source, not that no work exists.
Recent safety updates
- Contains Purified Mercury (Parada) and Purified Aconitum (Vatsanabha) - two highly toxic substances requiring extreme caution and strict medical supervision
- Mercury content poses risks of mercury bioaccumulation, neurological damage, and renal toxicity with improper dosing or prolonged use
- Vatsanabha (aconite) is one of the most toxic plants known; even after purification, cardiac toxicity risk exists at supra-therapeutic doses
- FDA and WHO have flagged mercury-containing Ayurvedic preparations; product quality varies widely between manufacturers
- Must be taken in precise dose (125-250 mg) for limited period only as prescribed; over-dosage can cause severe poisoning
- Iron overload is a minor concern relative to mercury and aconite toxicity; however, Loha Bhasma contribution still requires monitoring in patients with iron storage disorders
What is it made of?
Mineral/Elemental Profile
- Primary component: Mercury-based preparation (Parada) with herbal processing
- Note: Restricted use, requires strict Shodhana protocols and expert supervision
Dosage forms and preparation
Dosage Forms: Vati
Standard Dosage: 125–250 mg twice daily
Optimal Timing: Before meals with buttermilk or Vidanga Kwatha
Storage: Airtight container
Marker Compounds: Mercury sulfide, Iron oxide, Copper oxide, Embelin (Vidanga)
Vehicle (Anupana): Buttermilk, Vidanga Kwatha, or Palash seed powder
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Other clinical studies and reviews1
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.