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Eucalyptus

Eucalyptus globulus

Eucalyptus (Eucalyptus globulus) is a plant used in Ayurveda. Do not ingest undiluted essential oil. Bioavailability: Eucalyptus globulus essential oil is dominated by 1,8-cineole (eucalyptol, 60-85%). Cineole has excellent oral bioavailability (>70%) when given in enteric-coated form, with rapid absorption and distribution to respiratory tissues.

Key facts
Botanical nameEucalyptus globulus
Identity sourceAyurvedic Pharmacopoeia of India, Part I, Vol. V: TAILAPARNAH (Leaf)
Also calledEucalyptus polybractea / Eucalyptus smithii (and other cineole-rich species) (attribution recorded without a cited source)
Corymbia citriodora (syn. Eucalyptus citriodora Hook.) (attribution recorded without a cited source)
FamilyMyrtaceae · other entries in this family
OrderMyrtales
Taxon identifiersGBIF 3176787 · Wikidata Q159528 · NCBI Taxonomy 34317

Names and identification

LanguageName
EnglishEucalyptus

What is it made of?

Key Active Markers

  • Derived from constituent herbs (see individual herb profiles)
  • Standardized on primary bioactive markers

Analytical Methods: HPLC fingerprinting, TLC (identity), LC-MS/MS (marker quantification)

Dosage forms and preparation

Dosage Forms: Essential oil (primary), Inhalation (steam/vaporizer), Capsule (enteric-coated oil), Lozenge, Ointment/balm, Chest rub, Tincture

Standard Dosage: Essential oil: 2-4 drops for steam inhalation; 200-600mg cineole in enteric-coated capsules daily (divided doses); topical: 1-3% in carrier; lozenges: as directed. Do not ingest undiluted essential oil.

Bioavailability: Eucalyptus globulus essential oil is dominated by 1,8-cineole (eucalyptol, 60-85%). Cineole has excellent oral bioavailability (>70%) when given in enteric-coated form, with rapid absorption and distribution to respiratory tissues. Inhalation provides direct delivery to respiratory epithelium with systemic absorption via pulmonary circulation. Dermal absorption of cineole from topical preparations is moderate (5-10%) but sufficient for local anti-inflammatory and analgesic effects. First-pass metabolism is significant - enteric coating bypasses gastric degradation. Cineole is metabolized primarily by CYP3A4.

Optimal Timing: Steam inhalation: as needed for congestion, 2-3 times daily; oral capsules: after meals to reduce GI discomfort; topical: as needed, up to 3-4 times daily; chest rub: at bedtime

Standardized Extract: Essential oil: Ph. Eur. grade standardized to NLT 70% 1,8-cineole by GC-FID. Pharmaceutical isolate: 99%+ cineole (eucalyptol). Leaf dry extract: NLT 2% total polyphenols.

Shelf Life: 3-5 years (essential oil in sealed amber glass); 2 years (capsules); 2 years (ointment/balm); 3 years (lozenges)

Storage: Essential oil: tightly sealed amber glass bottles, cool dark place (15-25 deg C). Keep away from heat sources and open flame. Capsules: below 25 deg C in blister packs. Child-resistant closure mandatory.

Marker Compounds: 1,8-Cineole (eucalyptol), Alpha-pinene, Limonene, Alpha-terpineol, Globulol, Aromadendrene, p-Cymene

Extraction Methods

  • Steam distillation of fresh leaves (industrial standard)
  • Hydrodistillation
  • Supercritical CO2 extraction (premium quality)
  • Solvent extraction for oleoresin
  • Molecular distillation for pharmaceutical-grade cineole isolation

Synergistic Combinations

  • With Menthol (Pudina) for enhanced decongestant effect
  • With Camphor for chest rub formulations
  • With Tea tree oil for antimicrobial synergy
  • With Nilgiri Taila in traditional respiratory formulations
  • With Tulsi for immune-respiratory support

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