Dadrughna
Cassia tora L. (syn. Senna tora)
Dadrughna is a Sanskrit synonym of Chakramarda (Cassia tora L., syn. Senna tora, family Fabaceae) in Bhavaprakasha Nighantu and Raja Nighantu. Traditional practice emphasizes external application; data on internal use are limited.
| Substance type | Identity unsettled: the sources disagree on what this drug is, so no botanical name is given |
|---|---|
| Botanical name | Cassia tora L. (syn. Senna tora) |
| Currently accepted name | Senna tora (L.) Roxb., the name above is treated as a synonym by GBIF; both are in use |
| Family | Fabaceae · other entries in this family |
| Order | Fabales |
| Taxon identifiers | GBIF 5354127 · Wikidata Q21872227 · NCBI Taxonomy 362788 |
The evidence at a glance
12papers on this site for this drug, published 2004 to 2022, every one with a DOI.
- 2Other clinical studies and reviews
- 10Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Dadrughna |
Dadrughna is a Sanskrit synonym of Chakramarda (Cassia tora L., syn. Senna tora) in Bhavaprakasha Nighantu and Raja Nighantu (4.198-200); see that page for the fuller profile.
Ayurvedic pharmacology (Dravyaguna)
| Property | Value | Description |
|---|---|---|
| Rasa (Taste) | Katu | Primary taste |
| Guna (Quality) | Laghu, Ruksha | Physical quality |
| Virya (Potency) | Ushna | Heating/Cooling effect |
| Vipaka (Post-digestive) | Katu | Post-digestive effect |
Dosage forms and preparation
Dosage Forms: Lepa (topical paste), Taila (medicated oil), Churna (powder), Kashayam (decoction for external wash), Ointment
Standard Dosage: External use: paste applied to affected area 2-3 times daily; Internal: 3-5g powder twice daily with honey or warm water (limited internal use data)
Optimal Timing: Topical application after bathing on clean, dry skin; internal use before meals if prescribed
Storage: Cool, dry place away from direct sunlight. Topical preparations stored below 30 deg C. Fresh paste to be used within 24 hours of preparation.
Marker Compounds: Total phenolics (gallic acid equivalents), Flavonoids, Anthraquinones (where applicable)
Synergistic Combinations
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Other clinical studies and reviews2
- 2022. Preclinical activities of Cassia tora Linn against aging-related diseasesExpert reviews in molecular medicine. PMID 36281483 · doi:10.1017/erm.2022.33
- 2004. Antigenotoxic properties of Cassia tea (Cassia tora L.): mechanism of action and the influence of roasting processLife sciences. PMID 15501482 · doi:10.1016/j.lfs.2004.07.011
Laboratory and animal studies10
- 2022. Engineering properties of Cassia tora L. seeds and meal as a function of moisture contentScientific reports. PMID 35606481 · doi:10.1038/s41598-022-12748-7
- 2022. Green Synthesis and Characterisation of Silver Nanoparticles Using Cassia tora Seed Extract and Investigation of Antibacterial PotentialApplied biochemistry and biotechnology. PMID 34611854 · doi:10.1007/s12010-021-03651-4
- 2020. Synthesis and characterization of quaternized Cassia tora gum using Taguchi L'16 approachCarbohydrate polymers. PMID 31952579 · doi:10.1016/j.carbpol.2019.115731
- 2020. Cassia tora extract alleviates Aβ(1-42) aggregation processes in vitro and protects against aluminium-induced neurodegeneration in ratsThe Journal of pharmacy and pharmacology. PMID 32363579 · doi:10.1111/jphp.13283
- 2018. Editorial: The Potential Medicinal Uses of Cassia tora Linn Leaf and Seed ExtractsReviews on recent clinical trials. PMID 29469686 · doi:10.2174/157488711301180131145359
- 2017. Evaluation of Cassia tora Linn. against Oxidative Stress-induced DNA and Cell Membrane DamageJournal of pharmacy & bioallied sciences. PMID 28584491 · doi:10.4103/0975-7406.206215
- 2016. Polyphenols of Cassia tora leaves prevents lenticular apoptosis and modulates cataract pathology in Sprague-Dawley rat pupsBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. PMID 27261615 · doi:10.1016/j.biopha.2016.04.018
- 2016. Anthraquinones and flavonoids of Cassia tora leaves ameliorate sodium selenite induced cataractogenesis in neonatal ratsFood & function. PMID 26786764 · doi:10.1039/c5fo00905g
- 2012. Adulticidal and repellent properties of Cassia tora Linn. (Family: Caesalpinaceae) against Culex quinquefasciatus, Aedes aegypti, and Anopheles stephensiParasitology research. PMID 22821231 · doi:10.1007/s00436-012-3042-3
- 2007. Estrogenic and anti-estrogenic activities of Cassia tora phenolic constituentsChemical & pharmaceutical bulletin. PMID 17917292 · doi:10.1248/cpb.55.1476
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.