Age Ayurveda Nighantu

Avipattikar

Avipattikar is a compound formulation of several ingredients. Contains multiple herbs whose bioactives have varied absorption profiles. The formulation includes Trikatu (Pippali, Maricha, Sunthi) which acts as a built-in bioenhancer via piperine — this is a classical example of intelligent formulation design where bioenhancers are incorporated into the compound.

Key facts
Substance typeCompound formulation of several ingredients, not a single plant

Names and identification

LanguageName
EnglishAvipattikar

What is it made of?

Key Active Markers

  • Derived from constituent herbs (see individual herb profiles)
  • Standardized on primary bioactive markers

Analytical Methods: HPLC fingerprinting, TLC (identity), LC-MS/MS (marker quantification)

Dosage forms and preparation

Dosage Forms: Churna (compound powder), Tablet (compressed churna), Capsule

Standard Dosage: 3-6g churna with warm water or sugar cane juice before meals; 1-2 tablets (500mg each) twice daily

Bioavailability: This is a COMPOUND FORMULATION (not a single herb). Contains multiple herbs whose bioactives have varied absorption profiles. The formulation includes Trikatu (Pippali, Maricha, Sunthi) which acts as a built-in bioenhancer via piperine — this is a classical example of intelligent formulation design where bioenhancers are incorporated into the compound. Sugar/Mishri component provides quick energy substrate and palatability. Overall excellent bioavailability profile due to self-enhancing design.

Optimal Timing: Before meals (30 minutes) with warm water for hyperacidity; with sugar cane juice per classical texts; or after meals for post-prandial acid reflux

Standardized Extract: This is traditionally used as Churna (powder) rather than an extract. If extract is made: standardize to piperine content (from Trikatu component, minimum 1%), total tannin content (from Triphala, minimum 5%), and total volatile oil (from aromatic ingredients, minimum 0.3%).

Shelf Life: 2 years (churna); 3 years (tablets); 3 years (capsules)

Storage: Airtight container, cool and dry place. Contains hygroscopic sugar — moisture is the primary stability concern. Temperature below 25°C, RH < 55%.

Marker Compounds: Piperine (from Pippali/Maricha), Gallic acid (from Triphala), Chebulagic acid (from Haritaki), Embelin (from Vidanga), Eugenol (from Lavanga), 1,8-Cineole (from Ela)

Extraction Methods

  • Traditional: fine powdering and sequential mixing (Khalva Yantra trituration)
  • For tablet: direct compression of churna blend or wet granulation
  • For concentrated form: aqueous extraction of compound, spray-dried

Synergistic Combinations

  • This is itself a synergistic compound. Key synergies within: Trikatu enhances absorption of all other ingredients; Triphala provides digestive regulation; Vidanga provides anthelmintic action; Ela and Lavanga provide carminative action. External synergy: With Shatavari for Amlapitta with debility

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  • Acid ReliefTraditionally used to support comfortable digestion after meals.

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