Age Ayurveda Nighantu

Arka Ksheera

Arka Ksheera is a preparation made from plant material. Latex proteins (calotropain) are proteolytic and facilitate penetration through skin barriers. Shodhana (milk purification) process partially inactivates the most toxic cardenolides while retaining therapeutically useful compounds.

Key facts
Substance typePreparation made from plant material, not a single plant drug
Also known asArka Ksheera, ArkaKsheera

Names and identification

LanguageName
EnglishArka Ksheera

Ayurvedic pharmacology (Dravyaguna)

PropertyValueDescription
Rasa (Taste)Katu, TiktaPrimary taste
Guna (Quality)TikshnaPhysical quality
Virya (Potency)UshnaHeating/Cooling effect
Vipaka (Post-digestive)KatuPost-digestive effect

What is it made of?

Mineral/Elemental Profile

  • Primary component: Mineral-derived preparation
  • Note: Composition varies by specific preparation method

Analytical Methods: XRD, ICP-OES, SEM-EDS

Dosage forms and preparation

Dosage Forms: Processed latex (Shodhita Ksheera), Gutika (pills prepared with Shodhita latex), Taila (oil processed with latex — external), Lepa (paste — external)

Standard Dosage: 1-3 drops Shodhita latex with appropriate anupana (INTERNAL: only under strict physician supervision); external: as needed for topical application

Bioavailability: High bioavailability of cardiac glycosides from latex — calotropin and calactin are rapidly absorbed both orally and transdermally. Latex proteins (calotropain) are proteolytic and facilitate penetration through skin barriers. Shodhana (milk purification) process partially inactivates the most toxic cardenolides while retaining therapeutically useful compounds.

Optimal Timing: Strictly as per physician direction. External applications to affected area, avoiding broken skin and mucous membranes.

Standardized Extract: Shodhita Arka Ksheera (purified latex) with documented cardenolide content per batch. Total cardenolide levels must be within specified therapeutic range (established per classical formulation monograph).

Shelf Life: 1 year (Shodhita latex, refrigerated); 3 years (oil-based preparations); 2 years (pills/Gutika)

Storage: Shodhita latex refrigerated (2-8°C) in amber glass. Double-sealed containers. Clearly labeled: TOXIC — RESTRICTED. Store separately from food-grade materials.

Marker Compounds: Calotropin, Calactin, Calotoxin, Uscharin, Calotropagenin, Calotropain (protease)

Extraction Methods

  • Direct latex collection from stem incisions
  • Shodhana: trituration of latex with cow’s milk (Dugdha Bhavana, 7 cycles)
  • Oil processing (Ksheera added to sesame oil base with herbal decoction, heated per Taila Paka vidhi)

Synergistic Combinations

  • As component of Arka Taila for Vata disorders (external)
  • With processed Vatsanabha in highly specialized formulations (toxic combination — expert use only)
  • With Nirgundi Taila for musculoskeletal pain (external)

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