Amlaparni

Names and identification

Language	Name
English	Amlaparni
Latin/Botanical	Oxalis corniculata L.

Key Phytochemical Constituents

• Vitexin-2-O-beta-D-glucopyranoside
• Isovitexin
• Beta-sitosterol
• Betulin
• Apigenin
• Oxalic acid
• 4-Hydroxybenzoic acid
• Ethyl gallate
• Stearic acid
• Palmitic acid

How does it work?

• Flavonoids (vitexin, isovitexin, apigenin) exert antioxidant effects through direct free radical scavenging and chelation of pro-oxidant metal ions, reducing oxidative damage in cellular models
• Beta-sitosterol and betulin modulate inflammatory pathways by inhibiting NF-kB nuclear translocation and reducing expression of pro-inflammatory mediators (COX-2, iNOS, TNF-alpha)
• Ethyl gallate and phenolic compounds exhibit antimicrobial activity by disrupting bacterial cell membrane permeability and inhibiting biofilm formation

Which traditional uses are supported by research?

These summaries come from the source notes, which do not name the studies behind them.

• Amlaparni is traditionally used in Ayurveda in relation to blood sugar levels. In vivo studies have reported antidiabetic and hypoglycemic activity.
• Traditionally applied topically in folk medicine for skin conditions and wounds. Preclinical studies have reported wound healing activity.
• Traditionally used for liver disorders. Animal studies have reported hepatoprotective effects.

What do recent studies show?

• Zhong T, He J, Zhao H and others 2025. Oxalis corniculata L. As a Source of Natural Antioxidants: Phytochemistry, Bioactivities, and Application Potential. Antioxidants (Basel, Switzerland). PMID 41300509 · doi:10.3390/antiox14111352
  Comprehensive review highlighting flavonoids, polysaccharides, and organic acids as dominant metabolites with antioxidant, anti-inflammatory, antimicrobial, neuroprotective, hypoglycemic, and anticancer effects.
• Sarfraz I, Rasul A, Hussain G and others 2022. A Review on Phyto-pharmacology of Oxalis corniculata. Combinatorial chemistry & high throughput screening. PMID 34391377 · doi:10.2174/1386207324666210813121431
  Plant demonstrated significant hepatoprotective, antidiabetic, and wound healing activities in preclinical models, supporting traditional ethnomedicinal claims.

Only studies that could be traced to a published paper are listed here. An absence here means we could not identify the source, not that no work exists.

Recent safety updates

• High oxalic acid content is the primary safety concern; excessive consumption may cause oxalate nephropathy and kidney stone formation in susceptible individuals
• Traditional use suggests safe consumption in small therapeutic doses; no formal toxicity studies with standardized LD50 determination have been reported
• Should be used cautiously in patients with renal impairment, hyperoxaluria, or history of calcium oxalate kidney stones; further preclinical and clinical safety trials are recommended

Dosage forms and preparation

Dosage Forms: Churna (powder), Kashayam (decoction), Swarasa (fresh juice), Capsule, Tablet

Standard Dosage: 3-5g powder twice daily; 40-80ml decoction twice daily; 10-20ml fresh juice

Optimal Timing: Before meals with warm water for digestive indications; with honey for respiratory conditions

Storage: Cool, dry place below 25°C, in airtight containers, protected from moisture and light.

Marker Compounds: Total organic acids, Total phenolics, Total flavonoids, Ascorbic acid (if present)

Synergistic Combinations

• With Amalaki for enhanced sour/astringent synergy
• With Guduchi for immune support
• With Musta for digestive disorders