Amrita Ghrita
Amrita Ghrita is a classical Ayurvedic ghrita, a medicated ghee. Amrita (Guduchi) monograph in Ayurvedic Pharmacopoeia of India (API); Amrita Ghrita listed in Ayurvedic Formulary of India, Part I, entry 6:1; formulation standards regulated under PCIM&H. The Ayurvedic Formulary of India (Part I, entry 6:1) lists 4 ingredients: Amrta 1.536 kg, Water for decoction 12.288 l. reduced to 3.072 l, Mahausadha 128 g and Ghrta 768 g.
| Also known as | Amrita Ghrita, AmritaGhrita |
|---|---|
| Pharmacopoeia status | Amrita (Guduchi) monograph in Ayurvedic Pharmacopoeia of India (API); Amrita Ghrita listed in Ayurvedic Formulary of India, Part I, entry 6:1; formulation standards regulated under PCIM&H |
Composition
As given in the Ayurvedic Formulary of India, Part I, entry 6:1 (AMRTA GHRTA), which cites Cakradatta, Amavatacikitsa; 58.. Names, parts and quantities are transcribed as printed and checked row by row against the book. Manufacturers' versions of a classical formulation can differ from the formulary.
| # | Ingredient | Part | Quantity |
|---|---|---|---|
| 1 | Amrta (guduci) | stem | 1.536 kg. |
| 2 | Water for decoction | 12.288 l. reduced to 3.072 l. | |
| 3 | Mahausadha (Sunthi) | rhizome | 128 g. |
| 4 | Ghrta (go ghrta) | 768 g. |
The evidence at a glance
1paper on this site for this drug, every one with a DOI.
- 1Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people.true See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Amrita Ghrita |
Where is it described in the classical texts?
Cakradatta, Amavatacikitsa 58 (Amrita Ghrita; Ayurvedic Formulary of India, Part I, entry 6:1); Bhaishajya Ratnavali (Amrita Ghrita); Rasaratna Samuccaya; Yogaratnakara (preparations for enhancing Ojas); Ashtanga Hridayam (Amritaprasha Ghrita; Ayurvedic Formulary of India, Part I, entry 6:2, a separate formula)
How does it work?
- Guduchi (berberine, tinosporin) activates macrophages and enhances phagocytic activity, boosting innate immune response
- Tinospora polysaccharides stimulate both humoral and cell-mediated immunity, increasing immunoglobulin production
- Jeevaniya Gana herbs collectively provide Ojas-building and tissue-nourishing action across all seven Dhatus
- Adaptogenic herbs (Ashwagandha, Shatavari, Bala) modulate HPA axis, reducing stress-induced immunosuppression
- Ghee base delivers immunoactive compounds to deep tissues and enhances absorption of lipophilic phytochemicals
Which traditional uses are supported by research?
These summaries come from the source notes, which do not name the studies behind them.
- Vyadhikshamatva (immunity enhancement): traditionally used for enhancing immunity. A clinical study reported an increase in serum immunoglobulins in elderly subjects.
- Rasayana (rejuvenation): traditionally used for rejuvenation. Preclinical studies have reported immunomodulatory and adaptogenic activities.
- Jvara (fever): traditionally used for fever. Pharmacological studies have reported immunostimulant and antipyretic activities of Guduchi.
- Ojas Vardhana (vital energy enhancement): traditionally used for enhancing strength, immunity, and longevity.
What do recent studies show?
No study for this section could be traced to a published paper. Classical formulations are researched largely in journals that PubMed does not index, so an absence here reflects the reach of the index rather than the state of the evidence.
Recent safety updates
- A clinical study in elderly participants reported no adverse effects at 5ml daily for 8 weeks
- Guduchi generally recognized as safe with well-established toxicological profile; rare reports of autoimmune exacerbation in predisposed individuals
- Multiple ingredients require quality-assured sourcing; honey should not be heated above 40 degrees C per Ayurvedic principles
Dosage forms and preparation
Dosage Forms: Ghrita (medicated ghee), Soft gelatin capsules (modern)
Standard Dosage: 6-12 g (1-2 teaspoons) twice daily. The Ayurvedic Formulary of India attributes this formula to Cakradatta, Amavatacikitsa; 58.
Optimal Timing: On empty stomach, or as directed by physician
Storage: Store in airtight glass or tin-coated containers in a cool, dry place. Protect from moisture and light. Temperature not exceeding 25°C. Ghrita preparations are sensitive to oxidation.
Marker Compounds: Berberine, Tinosporaside, Columbin, 20-beta-hydroxyecdysone, Palmarin
Vehicle (Anupana): Warm water or warm milk
Synergistic Combinations
- Amritarishta
- Guduchi Satva
- Samshamani Vati
- Sudarshana Churna
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Laboratory and animal studies1
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
Educational reference only. Nothing on this page is medical advice, a diagnosis, or a recommendation to take anything. Traditional uses and research findings are reported as published, not as claims about what any product does. If you take prescribed medication, raise any interaction with the prescriber rather than acting on a page. See our editorial standards.