Tanduliyaka
Tanduliyaka is a substance used in the Ayurvedic materia medica. Polyphenols and flavonoids undergo extensive Phase II metabolism. The high dietary fiber content slows gastric emptying and may modulate absorption kinetics of co-administered drugs.
Names and identification
| Language | Name |
|---|---|
| English | Tanduliyaka |
Ayurvedic pharmacology (Dravyaguna)
| Property | Value | Description |
|---|---|---|
| Rasa (Taste) | Madhura | Primary taste |
| Guna (Quality) | Laghu, Ruksha | Physical quality |
| Virya (Potency) | Sheeta | Heating/Cooling effect |
| Vipaka (Post-digestive) | Madhura | Post-digestive effect |
What is it made of?
Mineral/Elemental Profile
- Primary component: Mineral-derived preparation
- Note: Composition varies by specific preparation method
Analytical Methods: XRD, ICP-OES, SEM-EDS
Dosage forms and preparation
Dosage Forms: Svarasa (fresh juice), Churna (powder), Kwatha (decoction), Capsule, Tablet
Standard Dosage: 10-20 mL fresh juice twice daily; 3-5 g powder twice daily; 50-100 mL decoction twice daily
Bioavailability: Betalains (amaranthine, isoamaranthine) show moderate oral bioavailability (~20-30%) with rapid absorption in the upper GI tract. Polyphenols and flavonoids undergo extensive Phase II metabolism. The high dietary fiber content slows gastric emptying and may modulate absorption kinetics of co-administered drugs. Iron and calcium from the plant matrix have moderate bioavailability enhanced by vitamin C co-administration.
Optimal Timing: Before meals for hematinic effect; morning administration with honey or jaggery as traditional vehicle
Standardized Extract: Aqueous or hydroethanolic extract standardized to >0.5% total betalains (as amaranthine by UV-Vis at 538 nm); >2% total polyphenols (as gallic acid equivalent)
Shelf Life: Fresh juice: 24-48 hours refrigerated; Powder: 12 months; Capsules/Tablets: 24 months; Spray-dried extract: 24 months
Storage: Store in airtight, light-resistant containers at 15-25 deg C. Betalain-containing products require protection from light, heat, and humidity. Freeze-dried forms stored at 2-8 deg C for maximum stability.
Marker Compounds: Amaranthine, Isoamaranthine, Rutin, Quercetin, Kaempferol, beta-Sitosterol, Gallic acid, Ferulic acid
Extraction Methods
- Aqueous extraction (decoction)
- Hydroethanolic extraction (40-60% ethanol)
- Cold pressing for fresh juice
- Spray drying of aqueous extract
- Freeze drying for color-sensitive betalains
Synergistic Combinations
- Amalaki (Emblica officinalis) - vitamin C enhances iron absorption from Tanduliyaka
- Shunthi - digestive enhancement and anti-inflammatory synergy
- Guduchi - immunomodulatory potentiation
- Jaggery - traditional vehicle for hematinic formulations
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