Talamuli
Curculigo orchioides
Talamuli (Curculigo orchioides) is a plant drug, also called Bhumitila, Kali musali and Syahmusali. Mucilaginous polysaccharides provide local GI effects (demulcent, prebiotic) rather than systemic absorption. Diosgenin derivatives are lipophilic and benefit from lipid-based formulations. Traditional Ghrita preparation enhances lipophilic constituent bioavailability by 2-3x.
| Botanical name | Curculigo orchioides |
|---|---|
| Family | Hypoxidaceae |
| Order | Asparagales |
| Taxon identifiers | GBIF 2853024 · Wikidata Q5194664 · NCBI Taxonomy 681286 |
| Sanskrit | Bhumitila, तालमूली (tālamūlī) |
|---|---|
| Hindi | काली मुसली (kālī musalī), Syahmusali |
| Tamil | Nilappanai, நிலப்பனைக்கிழங்கு |
| Malayalam | Nilappenea |
| Telugu | Nel tadigadda |
| Kannada | Nelatelegadde, Neltal, Neltathigodde |
| Marathi | Bhuimaddi, Kali musali |
| Bengali | Tallur, Talmalu |
| Gujarati | Kalirnusali |
| Urdu | Kali Musali, Musali Siyah |
| Punjabi | Musali safed, Syah musali |
| Oriya | Talamuli |
| Assamese | Talmuli |
Sources: Ayurvedic Pharmacopoeia of India (column alignment reconstructed); efloraofindia.com, Curculigo orchioides: Hindi 'काली मुसली kali musli', 'ताल मूली tal-muli'; efloraofindia.com, Curculigo orchioides: Sanskrit 'तालमूली talamuli', 'मुसली musali'; efloraofindia.com, Curculigo orchioides: Tamil 'நிலப்பனைக்கிழங்கு nilappanaikkilanku', 'நிலப்பனை nilappanai'. How we source.
The evidence at a glance
12papers on this site for this drug, published 2007 to 2025, every one with a DOI.
- 2Other clinical studies and reviews
- 10Laboratory and animal studies
A count is not a conclusion and a tier is a study design, not a verdict. Everything listed here is laboratory or animal work, which does not show an effect in people. Each paper is listed with what it measured on the page below. See the research index for how papers are tiered.
Names and identification
| Language | Name |
|---|---|
| English | Talamuli |
Ayurvedic pharmacology (Dravyaguna)
| Property | Value | Description |
|---|---|---|
| Rasa (Taste) | Madhura | Primary taste |
| Guna (Quality) | Guru, Snigdha | Physical quality |
| Virya (Potency) | Ushna | Heating/Cooling effect |
| Vipaka (Post-digestive) | Madhura | Post-digestive effect |
Dosage forms and preparation
Dosage Forms: Churna (powder), Kwatha (decoction), Swarasa (fresh juice), Capsule, Ghrita (medicated ghee), Leha/Avaleha (confection)
Standard Dosage: 3-6 g tuber powder per day; 10-20 mL swarasa twice daily; 50-100 mL kwatha twice daily; 500-1000 mg extract capsule twice daily
Optimal Timing: With warm milk at bedtime for Vajikarana action; morning dose with ghee for Rasayana (rejuvenative) effects
Storage: Swarasa: refrigerate 2-8 deg C. Churna: below 25 deg C in airtight containers with desiccant, hygroscopic. Capsules: standard storage below 25 deg C. Ghrita: glass jars at room temperature, protect from light.
Marker Compounds: Curculigoside, Curculigoside B, Curculigosaponin C, Curculigine, Diosgenin, Yuccagenin, Beta-sitosterol
Synergistic Combinations
- Shatavari (female reproductive tonic synergy)
- Vidari (Brihana, nourishing and anabolic combination)
- Ashwagandha (adaptogenic and Vajikarana synergy)
- Shvet-Musli (comprehensive Vajikarana formulation)
- Yashtimadhu (mucosal protective and cooling combination)
Published research
Literature indexed in PubMed that concerns this subject, grouped by study type. A paper appearing here is a record of what has been published, not evidence that the subject works, and laboratory or animal results do not transfer to people. Study titles link to PubMed so you can read the source rather than take our word.
Other clinical studies and reviews2
- 2013. Medicinal plants of genus Curculigo: traditional uses and a phytochemical and ethnopharmacological reviewJournal of ethnopharmacology. PMID 23562803 · doi:10.1016/j.jep.2013.03.066
- 2010. Curculigo orchioides: the black gold with numerous health benefitsZhong xi yi jie he xue bao = Journal of Chinese integrative medicine. PMID 20619136 · doi:10.3736/jcim20100703
Laboratory and animal studies10
- 2025. Cycloartane-type saponins from Curculigo orchioides and their anti-inflammatory activityRSC advances. PMID 41169998 · doi:10.1039/d5ra04849d
- 2023. Jinfeng pills ameliorate premature ovarian insufficiency induced by cyclophosphamide in rats and correlate to modulating IL-17A/IL-6 axis and MEK/ERK signalsJournal of ethnopharmacology. PMID 36775079 · doi:10.1016/j.jep.2023.116242
- 2023. Curculigo orchioides polysaccharide COP70-1 stimulates osteogenic differentiation of MC3T3-E1 cells by activating the BMP and Wnt signaling pathwaysInternational journal of biological macromolecules. PMID 37473884 · doi:10.1016/j.ijbiomac.2023.125879
- 2023. Protective Effect of Curculigo orchioides Gaertn. Extract on Heat Stress-Induced Spermatogenesis Complications in Murine ModelCurrent issues in molecular biology. PMID 37185736 · doi:10.3390/cimb45040212
- 2022. Toxicity Assessment of Curculigo orchioides Leaf Extract Using Drosophila melanogaster: A Preliminary StudyInternational journal of environmental research and public health. PMID 36429955 · doi:10.3390/ijerph192215218
- 2022. Discrimination of Curculigo orchioides Rhizoma and Curculigo glabrescens Rhizoma using stable isotope and mineral element analyses coupled with chemometricsScientific reports. PMID 35869256 · doi:10.1038/s41598-022-16851-7
- 2022. Analysis of a Major Phenolic Glucoside and Biochemistry Compounds from Curculigo Orchioides GaertnReports of biochemistry & molecular biology. PMID 35291616 · doi:10.52547/rbmb.10.4.565
- 2021. New chlorophenolic glycoside from Curculigo orchioides and their activities on 5α-reductaseJournal of Asian natural products research. PMID 32131631 · doi:10.1080/10286020.2020.1731800
- 2016. Curculigo orchioides Gaertn Effectively Ameliorates the Uro- and Nephrotoxicities Induced by Cyclophosphamide Administration in Experimental AnimalsIntegrative cancer therapies. PMID 26424815 · doi:10.1177/1534735415607319
- 2007. Evaluation of estrogenic activity of alcoholic extract of rhizomes of Curculigo orchioidesJournal of ethnopharmacology. PMID 17900835 · doi:10.1016/j.jep.2007.08.009
Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.
Consult a qualified vaidya before acting on anything here. Ayurvedic practice is prescribed to a person, not to a condition: the same dravya is given, withheld or substituted depending on your constitution, your agni, the season and what else you are already taking. A page cannot know any of that. Self-prescribing from a reference is how the wrong preparation, the wrong dose or the wrong anupana gets used.
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