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Devadali

Devadali is a substance used in the Ayurvedic materia medica. Cucurbitacins are lipophilic triterpenoids that absorb well from the GI tract but undergo hepatic metabolism. Fresh juice (Swarasa) provides highest bioavailability of volatile and labile constituents.

Names and identification

LanguageName
EnglishDevadali

Ayurvedic pharmacology (Dravyaguna)

PropertyValueDescription
Rasa (Taste)Tikta, KatuPrimary taste
Guna (Quality)Laghu, TikshnaPhysical quality
Virya (Potency)UshnaHeating/Cooling effect
Vipaka (Post-digestive)KatuPost-digestive effect

Dosage forms and preparation

Dosage Forms: Swarasa (fresh juice), Churna (powder), Kashayam (decoction), Tablet, Capsule

Standard Dosage: 5-10ml fresh juice twice daily; 3-6g powder twice daily; 50-100ml decoction twice daily; 500mg extract capsule twice daily

Optimal Timing: Before meals with warm water; fresh juice on empty stomach

Storage: Powder and extracts: airtight containers below 25 deg C, protected from moisture and light. Fresh material: refrigerate at 2-8 deg C.

Marker Compounds: Cucurbitacin B, Cucurbitacin E, Colocynthin, Saponins, Luffin (ribosome-inactivating protein)

Synergistic Combinations

  • With Katuki (Picrorhiza) for hepatoprotective synergy
  • With Haritaki, traditionally used as a purgative
  • With Bhringaraj, traditionally used for jaundice
  • With Punarnava, traditionally combined for hepatorenal support

Reviewed by Dr. Awadesh Pratap Singh, BAMS, on 11 October 2026. What that review covered.

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