Guggulu Herb
Guggulu Herb is a classical Ayurvedic guggulu, a resin-based preparation. Shodhana processing removes irritant oleoresin components while retaining guggulsterones. Purified guggulu has significantly improved safety and moderate oral bioavailability of guggulsterones.
| Also known as | Guggulu Herb, GugguluHerb |
|---|
Names and identification
| Language | Name |
|---|---|
| English | Guggulu_Herb |
What is it made of?
Key Active Markers
- Derived from constituent herbs (see individual herb profiles)
- Standardized on primary bioactive markers
Analytical Methods: HPLC fingerprinting, TLC (identity), LC-MS/MS (marker quantification)
Dosage forms and preparation
Dosage Forms: Raw resin (for processing), Shuddha Guggulu|Shuddha Guggulu (purified), Powder, Capsules (modern)
Standard Dosage: Only as Shuddha (purified) form: 250-500 mg twice daily, as per API/AFI
Bioavailability: Raw resin has poor bioavailability and contains irritant fractions. Shodhana processing removes irritant oleoresin components while retaining guggulsterones. Purified guggulu has significantly improved safety and moderate oral bioavailability of guggulsterones.
Optimal Timing: After Shodhana, as directed in specific Guggulu formulations
Shelf Life: Raw resin: 5+ years if stored properly; Purified: 5 years
Storage: Store raw resin in airtight containers away from heat and sunlight. Dried resin is hard and brittle — store in cloth bags in cool, dry place. Temperature not exceeding 30°C.
Marker Compounds: Z-Guggulsterone, E-Guggulsterone, Guggulsterol I-III, Myrrhanol A, Cembrene, Mukulol
Quality Parameters: Total guggulsterones (Z + E) NLT 2.5%, volatile oil content, water-soluble extractive, alcohol-soluble extractive, total ash, foreign organic matter, moisture, HPTLC/HPLC fingerprint, heavy metals, microbial limits
Vehicle (Anupana): Must be processed (Shodhana) before use — not taken as raw herb
Synergistic Combinations
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