# Nirgundi Herb

Canonical version of this page: https://nighantu.ageayurveda.com/herb/nirgundi-herb/

> Nirgundi Herb (Vitex negundo) is a plant drug, also called Nirgundi. Iridoid glycosides (agnuside, aucubin) have moderate oral bioavailability (20-35%). Lignans from stem bark are absorbed more slowly (Tmax 3-4 h) providing sustained activity.

## Key facts

- **Botanical name:** Vitex negundo
- **Family:** Lamiaceae

## Names in the Indian languages

Every name form this project holds for this drug, with the script form first and the
transliteration after it. Sources per name are on the canonical page.

| Language | Names |
| --- | --- |
| Hindi | निर्गुण्डी (nirguṇḍī) |
| Tamil | நொச்சி, வெண்ணொச்சி |

## Names and identification

| Language | Name |
|----------|------|
| English | Nirgundi Herb |

## Dosage forms and preparation

**Dosage Forms:** Churna (whole herb powder), Kwatha (decoction), Capsule, Tablet, Taila (medicated oil), [Ghrita](/herb/ghrita/) (medicated ghee), Swarasa, External poultice

**Standard Dosage:** 2-4 g whole herb powder daily in divided doses; 15-30 mL decoction twice daily; 500 mg - 1 g standardized whole herb extract twice daily

**Optimal Timing:** Oral preparations: after meals. Taila/external application: before bath or at bedtime. [Ghrita](/herb/ghrita/): on empty stomach with warm water for systemic Vata management.

**Storage:** Dried herb: well-ventilated, airtight containers, below 25 deg C, RH <55%. Ghrita: clean, dry glass or food-grade containers, below 30 deg C, protect from moisture. Taila: amber glass, room temperature.

**Marker Compounds:** Agnuside, Aucubin, Casticin, [Vitexin](/glossary/compounds-t-z/#vitexin), [Luteolin](/glossary/compounds-l-o/#luteolin)-7-glucoside, Lignan glycosides, Beta-[sitosterol](/glossary/compounds-q-t/#sitosterol), p-Hydroxybenzoic acid

### Synergistic Combinations

- Dashmool combination (10-root formulation for Vata disorders)
- Maharasnadi Kwatha ingredients (comprehensive musculoskeletal formula)
- [Bala](/herb/bala/) (muscle strength and nerve health)
- [Punarnava](/herb/punarnava/) (anti-edema and [diuretic](/reference/diuretic/) combination)
- [Guduchi](/herb/guduchi/) (immune modulation with pain relief)

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Canonical version of this page: https://nighantu.ageayurveda.com/herb/nirgundi-herb/

## Sources

- Amidha Ayurveda Herb Database (700+ herbs, CC-BY-4.0)
- Ayurvedic Pharmacopoeia of India

Published by Age Ayurveda in the Nighantu. Educational reference only, not medical advice.
Incorporates material from the Amidha Ayurveda Herb Database under CC BY 4.0.