# Godanti Bhasma

> Godanti Bhasma is a bhasma, a mineral or metal preparation reduced to ash by repeated calcination. An absence here means we could not identify the source, not that no work exists. SAFE: LD50 in Class IV (>2000 mcg/kg) indicating low acute toxicity.

## Names and identification

| Language | Name |
|----------|------|
| English | [Godanti Bhasma](/herb/godanti-bhasma/) |

## Key Phytochemical Constituents

- Calcium sulfate (CaSO4) as primary constituent
- Calcium oxide (CaO) from decomposition during calcination
- [Silicon](/glossary/compounds-q-t/#silicon) dioxide traces
- [Magnesium](/glossary/compounds-l-o/#magnesium), [strontium](/glossary/compounds-q-t/#strontium) as trace elements
- Organic residues from herbal processing media

## How does it work?

- [Antipyretic](/reference/antipyretic/) action through prostaglandin synthesis inhibition and thermoregulatory center modulation, effectively reducing yeast-induced hyperpyrexia in animal models
- Gastroprotective effect through acid neutralization by calcium compounds and cytoprotective enhancement of gastric mucosal barrier against stress and NSAID-induced ulceration
- Calcium supplementation through bioavailable calcium sulfate providing elemental calcium for bone metabolism, muscle function, and nerve transmission
- Pitta-shamaka (cooling) action through alkaline pH buffering and reduction of inflammatory heat, addressing Pitta-predominant conditions systemically

## Which traditional uses are supported by research?

- Fever (Jwara): Significant antipyretic activity demonstrated in yeast-induced fever model, validating traditional anti-fever indication
- Peptic ulcer and gastritis (Amlapitta): 44-45% gastroprotection in experimental ulcer models validates traditional use for acid-related disorders
- Calcium deficiency and bone disorders: Bioavailable calcium content supports traditional use for Asthi Kshaya (bone depletion) conditions

## What do recent clinical trials show?



*3 further claims previously listed here could not be traced to a published paper and have been removed. An absence here means we could not identify the source, not that no work exists.*

## Recent safety updates

- SAFE: LD50 in Class IV (>2000 mcg/kg) indicating low acute toxicity. Very safe in dose-dependent manner.
- NO HEAVY METAL RISK: Calcium sulfate-based preparation without toxic heavy metals (lead, mercury, arsenic). One of the safest Bhasma preparations.
- PREGNANCY CAUTION: Best avoided during pregnancy and in infants. Can be administered in lower doses to lactating mothers and children.
- HYPERCALCEMIA RISK: Excessive use may lead to elevated calcium levels. Appropriate dose monitoring recommended for prolonged use.

## What is it made of?

### Mineral/Elemental Profile

- **Calcium sulfate (CaSO4):** Major component (gypsum-derived)
- **Calcium (Ca):** 23.3%
- **Sulfur (S):** 18.6%
- **Oxygen:** 55.8%

**Analytical Methods:** XRD, FTIR, ICP-OES

## Dosage forms and preparation

**Dosage Forms:** Bhasma

**Standard Dosage:** 250–500 mg twice daily

**Bioavailability:** Good; calcium sulfate converted to bioavailable calcium form through calcination

**Optimal Timing:** With meals for calcium absorption; empty stomach for fever

**Standardized Extract:** Calcined gypsum bhasma

**Shelf Life:** Indefinite

**Storage:** Airtight container; moisture-sensitive

**Marker Compounds:** Calcium sulfate (primary), Calcium oxide, Trace minerals

**Quality Parameters:** Varitaratva, Rekhapurnatva, calcium content >25%, heavy metals within limits

**Vehicle (Anupana):** Honey for fever; ghee for calcium supplementation

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Canonical version of this page: https://nighantu.ageayurveda.com/herb/godanti-bhasma/

## Sources

- Amidha Ayurveda Herb Database (700+ herbs, CC-BY-4.0)
- Web research (clinical trials, WHO monographs, safety databases)
- Ayurvedic Pharmacopoeia of India

Published by Age Ayurveda in the Nighantu. Educational reference only, not medical advice.
Incorporates material from the Amidha Ayurveda Herb Database under CC BY 4.0.