# Sanjivani Vati

> Sanjivani Vati is a classical Ayurvedic vati, a herbal tablet or pill. Classical formulations are researched largely in journals that PubMed does not index, so an absence here reflects the reach of the index rather than the state of the evidence.

## Key facts

- **Pharmacopoeia status:** Listed in Ayurvedic Formulary of India (AFI) Part I; classified under Schedule E(1) of Drugs and Cosmetics Act (contains Vatsanabha - requiring controlled dispensing); recognized by CCRAS; quality standards defined for Shuddha Vatsanabha and Shuddha Bhallataka processing

## Names and identification

| Language | Name |
|----------|------|
| English | [Sanjivani Vati](/formulation/sanjivani-vati/) |

## Where is it described in the classical texts?

Sharangdhara Samhita (Madhyama Khanda); also described in Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya with references dating to approximately 500 CE; prominently featured in Bhaishajya Ratnavali

## How does it work?

- Ama Pachana (toxin digestion): Katu (pungent) and Tikta (bitter) Rasa with light, sharp, dry qualities and warm potency collectively digest metabolic toxins (Ama) and prevent further formation by correcting Mandagni
- Diaphoretic [antipyretic](/reference/antipyretic/): The formulation induces perspiration, breaks the fever cycle, and reduces body temperature through peripheral vasodilation and enhanced heat dissipation
- [Antimicrobial](/reference/antimicrobial/) defense: [Vidanga](/herb/vidanga/) ([embelin](/glossary/compounds-d-g/#embelin)), [Vacha](/herb/vacha/) (beta-asarone), and [Guduchi](/herb/guduchi/) demonstrate activity against Salmonella typhi, H. pylori, and other enteric pathogens
- Immunomodulation: [Guduchi](/herb/guduchi/) (Tinospora cordifolia) as an adaptogen and immunomodulator enhances overall immunity and manages chronic fevers and infections through upregulation of phagocytic activity
- Toxin neutralization (Vishaghna): Shuddha [Vatsanabha](/herb/vatsanabha/) (processed aconite) in micro-doses acts as a powerful Vishaghna (antitoxin) while processed Bhallataka provides antirheumatic and immune-stimulant action

## Which traditional uses are supported by research?

- Fever management (Jwara Chikitsa) validated through demonstrated diaphoretic and antipyretic mechanisms breaking fever cycle
- Toxin elimination (Ama Pachana/Vishaghna) validated through antimicrobial activity against Salmonella typhi and H. pylori and cellular-level metabolic correction
- Gastro-enteritis (Visuchika) management validated through combined antimicrobial, anti-inflammatory, and digestive-correcting actions
- Immunomodulation validated through [Guduchi](/herb/guduchi/)'s demonstrated enhancement of phagocytic activity and adaptive immune response

## What do recent clinical trials show?



*3 further claims previously listed here could not be traced to a published paper and have been removed. Classical formulations are researched largely in journals that PubMed does not index, so an absence here reflects the reach of the index rather than the state of the evidence.*

## Recent safety updates

- Contains Shuddha [Vatsanabha](/herb/vatsanabha/) (purified aconite) and Shuddha Bhallataka (purified marking nut) which are toxic in unpurified form - MUST be prepared strictly according to classical Shodhana protocols; use only under qualified Ayurvedic physician supervision
- Contraindicated in pregnancy, lactation, and young children; avoid in Pitta-predominant conditions; therapeutic dose must be strictly adhered to; overdose can be dangerous; not for self-medication or OTC purchase; short-term use during acute conditions recommended

## What is it made of?

### Mineral/Elemental Profile

- **Primary component:** Mineral-derived preparation
- **Note:** Composition varies by specific preparation method

**Analytical Methods:** XRD, ICP-OES, SEM-EDS

## Dosage forms and preparation

**Dosage Forms:** Vati (pill/tablet), Capsule

**Standard Dosage:** 1-2 tablets twice daily

**Bioavailability:** Tablet/pill form provides controlled disintegration; some vatis use honey/[guggulu](/formulation/guggulu/) as bioenhancing binders

**Optimal Timing:** Before or after meals as indicated

**Shelf Life:** 2 years per ASU guidelines for vati

**Storage:** Airtight container, cool dry place, protected from moisture

**Marker Compounds:** Embelin, [Tinosporin](/glossary/compounds-t-z/#tinosporin), [Piperine](/reference/piperine/)

**Quality Parameters:** Weight variation ±5%, disintegration <30 min, friability <1%, marker: Embelin, Tinosporin, Piperine

**Vehicle (Anupana):** Warm water or as specified

### Synergistic Combinations

- Key herbs: [Vidanga](/herb/vidanga/), [Guduchi](/herb/guduchi/), Shunthi, [Pippali](/herb/pippali/), [Vacha](/herb/vacha/)

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Canonical version of this page: https://nighantu.ageayurveda.com/formulation/sanjivani-vati/

## Sources

- Amidha Ayurveda Herb Database (700+ herbs, CC-BY-4.0)
- Web research (clinical trials, WHO monographs, safety databases)
- Ayurvedic Pharmacopoeia of India
- Classical Ayurvedic texts (Charaka Samhita, Sushruta Samhita, Bhavaprakasha Nighantu)

Published by Age Ayurveda in the Nighantu. Educational reference only, not medical advice.
Incorporates material from the Amidha Ayurveda Herb Database under CC BY 4.0.